Vital-D 200 IU/ml (Pediatric Drops)
15 ml bottle: ৳ 75.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Cholecalciferol vitamin d3 |
| Company | Unimed unihealth pharmaceuticals ltd |
| Also available as |
Indications
- Prevention of Vitamin D3 deficiency
- Treatment of Vitamin D3 deficiency
- Prevention of rickets
- Prevention of osteomalacia
- Prevention of osteoporosis
- Prevention of pre-eclampsia during pregnancy
- Immunity boost
Pharmacology
- Active form: Calcitriol
- Binds to Vitamin D receptors (VDRs)
- Half-life of about 50 days
- Fat soluble
- Absorbed in the small intestine
- Metabolized to 25-hydroxy Vitamin D3 (Calcidiol)
- Second hydroxylation to 1,25-dihydroxy Vitamin D3 (Calcitriol) in the kidney
- Increases calcium absorption
- Stored in tissues such as fat and muscle
- Eliminated via faeces and urine
Dosage & Administration
- Adult dosage: 40000 IU once weekly for 7 weeks
- Maintenance therapy dosage: 1400-2000 IU/day
- Children (12-18 years) dosage: 20000 IU once every 2 weeks for 6 weeks
- Daily tablet dosage: 1000 IU (1-2 tablets)
- Syrup dosage for patients with risk of Cholecalciferol deficiency
Interaction
- Drugs causing Vitamin D3 deficiencies
- Interference with absorption and metabolism
- Examples: Magnesium containing Antacids, Digoxin, Thiazide Diuretics, Cholestyramine, Corticosteroids
Contraindications
- Hypercalcaemia
- Hypersensitivity to Vitamin D3
- Evidence of Vitamin D3 toxicity
Side Effects
- Anorexia
- Lassitude
- Nausea & vomiting
- Diarrhea
- Constipation
- Weight loss
- Polyuria
- Sweating
- Headache
- Thirst
- Vertigo
- Raised concentrations of calcium and phosphate in plasma and urine
Pregnancy & Lactation
- Safe use up to 4000 IU during pregnancy
- Recommended daily intake for pregnant women: 400 IU
- Excretion in breast milk
- No observed overdose in nursing infants
Precautions & Warnings
- Monitor plasma-calcium concentration
- Consult a health care practitioner before supplementing with Vitamin D3 in specific conditions
- Renal impairment
- Liver or kidney disease
- Primary hyperthyroidism
- Lymphoma
- Tuberculosis
- Granulomatous disease
Use in Special Populations
- Safety & efficacy in children under 12 years not established
Overdose Effects
- Hypervitaminosis D
Therapeutic Class
- Vitamin in bone formation
- Vitamin-D preparations
Storage Conditions
- Keep below 30°C temperature
- Protected from light & moisture
- Keep out of the reach of children