Vital-D 200 IU/ml (Pediatric Drops)

15 ml bottle: ৳ 75.00

Medicine Details

Category Details
Generic Cholecalciferol vitamin d3
Company Unimed unihealth pharmaceuticals ltd
Also available as
Vital d 20000 iu capsule Vital d 40000 iu capsule Vital d 1000 iu capsule Vital d 2000 iu capsule Vital d 10000 iu oral solution

Indications

  • Prevention of Vitamin D3 deficiency
  • Treatment of Vitamin D3 deficiency
  • Prevention of rickets
  • Prevention of osteomalacia
  • Prevention of osteoporosis
  • Prevention of pre-eclampsia during pregnancy
  • Immunity boost

Pharmacology

  • Active form: Calcitriol
  • Binds to Vitamin D receptors (VDRs)
  • Half-life of about 50 days
  • Fat soluble
  • Absorbed in the small intestine
  • Metabolized to 25-hydroxy Vitamin D3 (Calcidiol)
  • Second hydroxylation to 1,25-dihydroxy Vitamin D3 (Calcitriol) in the kidney
  • Increases calcium absorption
  • Stored in tissues such as fat and muscle
  • Eliminated via faeces and urine

Dosage & Administration

  • Adult dosage: 40000 IU once weekly for 7 weeks
  • Maintenance therapy dosage: 1400-2000 IU/day
  • Children (12-18 years) dosage: 20000 IU once every 2 weeks for 6 weeks
  • Daily tablet dosage: 1000 IU (1-2 tablets)
  • Syrup dosage for patients with risk of Cholecalciferol deficiency

Interaction

  • Drugs causing Vitamin D3 deficiencies
  • Interference with absorption and metabolism
  • Examples: Magnesium containing Antacids, Digoxin, Thiazide Diuretics, Cholestyramine, Corticosteroids

Contraindications

  • Hypercalcaemia
  • Hypersensitivity to Vitamin D3
  • Evidence of Vitamin D3 toxicity

Side Effects

  • Anorexia
  • Lassitude
  • Nausea & vomiting
  • Diarrhea
  • Constipation
  • Weight loss
  • Polyuria
  • Sweating
  • Headache
  • Thirst
  • Vertigo
  • Raised concentrations of calcium and phosphate in plasma and urine

Pregnancy & Lactation

  • Safe use up to 4000 IU during pregnancy
  • Recommended daily intake for pregnant women: 400 IU
  • Excretion in breast milk
  • No observed overdose in nursing infants

Precautions & Warnings

  • Monitor plasma-calcium concentration
  • Consult a health care practitioner before supplementing with Vitamin D3 in specific conditions
  • Renal impairment
  • Liver or kidney disease
  • Primary hyperthyroidism
  • Lymphoma
  • Tuberculosis
  • Granulomatous disease

Use in Special Populations

  • Safety & efficacy in children under 12 years not established

Overdose Effects

  • Hypervitaminosis D

Therapeutic Class

  • Vitamin in bone formation
  • Vitamin-D preparations

Storage Conditions

  • Keep below 30°C temperature
  • Protected from light & moisture
  • Keep out of the reach of children

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