Vital-D 2000 IU (Capsule)

Unit Price: ৳ 10.00 (3 x 10: ৳ 300.00)
Strip Price: ৳ 100.00

Medicine Details

Title and Categories

  • Vitamin D3 Supplement
  • Vitamin-D Preparations
  • Calcitriol Supplement

Color Options

  • White

Dosage Forms

  • Capsule
  • Film-coated tablet
  • Oroflash or chewable tablets
  • Syrup
  • Injection

Dosage Recommendations

  • 40000 IU once weekly for 7 weeks for adults for Vitamin D3 deficiency
  • 1400-2000 IU/day for maintenance therapy for adults
  • 20000 IU every 4 weeks for prevention of Vitamin D3 deficiency in adults
  • 20000 IU once a month as addition to specific therapy for osteoporosis in adults
  • 20000 IU once every 2 weeks for 6 weeks for Vitamin D3 deficiency in children (12-18 years)
  • 20000 IU every 6 weeks for prevention of Vitamin D3 deficiency in children (12-18 years)

Usability Features

  • Take with food or within 1 hour after a meal for certain dosage forms
  • Place the tablet in mouth and swallow after chewing for oroflash or chewable tablets

Storage Information

  • Keep below 30° C temperature
  • Protected from light & moisture
  • Keep out of the reach of children

Pharmacology

  • Active form: Calcitriol
  • Half-life: About 50 days
  • Absorbed in small intestine
  • Metabolism to 25-hydroxy Vitamin D3 in liver
  • Second hydroxylation to 1,25-dihydroxy Vitamin D3 in kidney

Interaction

  • Drugs causing Vitamin D3 deficiencies: Magnesium containing Antacids, Digoxin, Thiazide Diuretics, Cholestyramine, Cholistipol, Phenytoin, Phenobarbital, Orlistat, Mineral Oil, Corticosteroids
  • Corticosteroids increase the need for Vitamin D3

Contraindications

  • Diseases associated with hypercalcaemia
  • Known hypersensitivity to Vitamin D3 or its class
  • Evidence of Vitamin D3 toxicity

Side Effects

  • Anorexia
  • Lassitude
  • Nausea & vomiting
  • Diarrhea
  • Constipation
  • Weight loss
  • Polyuria
  • Sweating
  • Headache
  • Thirst
  • Vertigo
  • Raised concentrations of calcium and phosphate in plasma and urine

Pregnancy & Lactation

  • Safe use of doses up to 4000 IU during pregnancy
  • Recommended daily intake for pregnant women: 400 IU
  • Excretion of Vitamin D3 and its metabolites in breast milk
  • Consideration of additional vitamin D3 doses for breast-fed child

Precautions & Warnings

  • Plasma-calcium concentration monitoring for patients receiving high doses
  • Consultation before supplementing with Vitamin D3 for individuals using Digoxin and Thiazide Diuretics
  • Consultation before supplementing with Vitamin D3 for individuals with liver or kidney disease, primary hyperthyroidism, lymphoma, tuberculosis, and granulomatous disease

Use in Special Populations

  • Safety & efficacy not established in children under 12 years

Overdose Effects

  • Hypervitaminosis D

Therapeutic Class

  • Vitamin in bone formation
  • Vitamin-D preparations

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