Vorifend 200 mg (Tablet)
Unit Price: ৳ 130.00 (1 x 10: ৳ 1,300.00)
Strip Price: ৳ 1,300.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Voriconazole |
| Company | Unimed unihealth pharmaceuticals ltd |
Indications
- Invasive aspergillosis
- Candidemia
- Disseminated candidiasis
- Esophageal candidiasis
- Serious infections caused by Scedosporium apiospermum
- Fusarium species infections
- Patients intolerant of other therapy
Pharmacology
- Triazole antifungal medication
- Binds and inhibits ergosterol synthesis
- Inhibits CYP450-dependent 14-alpha sterol demethylase
Dosage & Administration
- Oral administration
- Loading dose regimen for body weight over 40 kg
- Maintenance dose regimen for body weight over 40 kg
- Loading dose regimen for body weight below 40 kg
- Maintenance dose regimen for body weight below 40 kg
- Injection dosage for invasive aspergillosis
- Injection dosage for candidemia in nonneutropenic patients
- Injection dosage for Scedosporiosis and Fusariosis
Interaction
- CYP3A4, CYP2C9 and CYP2C19 inhibitors and inducers
- Increased concentrations and activity of drugs
- Co-administration with Phenytoin or Efavirenz
Contraindications
- Hypersensitivity to Voriconazole or components
- Co-administration with specific drugs due to risk of adverse reactions or loss of efficacy
Side Effects
- Abdominal pain
- Anemia
- Blurred vision
- Headache
- Chest pain
- Nausea
- Diarrhea
Pregnancy & Lactation
- No well-controlled studies in pregnant women
- Use during pregnancy only if potential benefit justifies potential risk to fetus
Precautions & Warnings
- Long term exposure assessment
- Reported occurrence of squamous cell carcinoma of the skin
- Special precautions for treatment duration over 180 days
Use in Special Populations
- Efficacy not established for children under 12 years of age
Overdose Effects
- No available data on Voriconazole overdose effects
Therapeutic Class
- Other Antifungal preparations
Reconstitution
- Instructions for suspension reconstitution
- Shelf-life of reconstituted suspension
Storage Conditions
- Keep out of reach of children
- Store in a dry place below 25°C temperature and protected from light
- Specific storage temperature for Voriconazole powder for suspension