Alurol 100 mg (Tablet)
Unit Price: ৳ 4.00 (10 x 10: ৳ 400.00)
Strip Price: ৳ 40.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Allopurinol |
| Company | Incepta pharmaceuticals ltd |
Indications
- Reduction of urate/uric acid formation
- Treatment of gouty arthritis
- Management of skin tophi
- Management of nephrolithiasis
- Management of 2,8-dihydroxyadenine (2,8-DHA) renal stones
Pharmacology
- Xanthine oxidase inhibitor
- Orally administered
- Acts on purine catabolism
- Reduces production of uric acid
- Structural analogue of hypoxanthine
Dosage & Administration
- Initial dosage: 100mg/day for adults
- Dosage increase based on serum urate response
- Caution in poor renal function
- Dosage ranges for different conditions
- Dosage for children: 10 to 20 mg/kg body weight/day
Interaction
- Interactions with 6-mercaptopurine and azathioprine
- Enhanced toxic effects with vidarabine
- Monitoring theophylline levels
- Skin rash reports with ampicillin or amoxicillin
Contraindications
- Contradicted in known hypersensitivity to allopurinol
Side Effects
- Rashes
- Gastrointestinal disorders
- Malaise
- Headache
- Vertigo
- Drowsiness
- Hypertension
- Alopecia
- Hepatotoxicity
- Neuropathy
- Gynecomastia
- Blood disorders
Pregnancy & Lactation
- Inadequate evidence of safety in human pregnancy
- Use only when no safer alternative
- No data on effects on breastfed baby
Precautions & Warnings
- Immediate withdrawal with skin rash
- Reduced doses in hepatic or renal impairment
- Caution in patients with hypertension or cardiac insufficiency
Overdose Effects
- Ingestion of up to 22.5g without adverse effects
- Symptoms include nausea, vomiting, diarrhea, dizziness
- Adequate hydration for optimum diuresis
- Consideration of hemodialysis if necessary
Therapeutic Class
- Drugs used in Gout
Storage Conditions
- Keep below 30°C
- Away from light & moisture
- Keep out of the reach of children