Carmapine 200 mg (Tablet)

Unit Price: ৳ 4.00 (5 x 10: ৳ 200.00)
Strip Price: ৳ 40.00

Medicine Details

Category Details
Generic Carbamazepine
Company Incepta pharmaceuticals ltd
Also available as
Carmapine 100 mg suspension Carmapine cr 200 mg tablet

Indications

  • Partial and secondary generalized tonic-clonic seizures
  • Primary generalized tonic-clonic seizures
  • Trigeminal neuralgia
  • Prophylaxis of bipolar disorder

Pharmacology

  • Depresses activity in the nucleus ventralis of the thalamus
  • Reduces synaptic propagation of excitatory impulses
  • Decreases summation of temporal stimulation leading to neural discharge by limiting influx of Na ions across cell membrane
  • Stimulates the release of antidiuretic hormone (ADH)

Dosage & Administration

  • Initial dosage for adults and children over 12 years of age
  • Initial dosage for children 12-15 years of age
  • Initial dosage for children 6-12 years of age
  • Initial dosage for children under 6 years of age
  • Combination therapy
  • Trigeminal Neuralgia initial dosage
  • Trigeminal Neuralgia maintenance dosage

Interaction

  • Galactorrhoea reported in few women on oral contraceptives
  • Hepatic enzyme inducers interaction with Carmapine

Contraindications

  • Allergic to one or any of its ingredients
  • Problems with the electrical message pathways in the heart
  • History of decreased blood cell production by the bone marrow
  • Hereditary blood disorders called porphyrias
  • Allergy to tricyclic antidepressants
  • Recent monoamine-oxidase inhibitor antidepressant (MAOI) use

Side Effects

  • Dizziness
  • Drowsiness
  • Ataxia
  • Dry mouth
  • Abdominal pain
  • Nausea
  • Vomiting
  • Leucopenia
  • Proteinuria
  • Bradycardia
  • Heart failure
  • Hypotension
  • Erythematous skin rash
  • Aplastic anemia
  • Increased sensitivity to the sun

Pregnancy & Lactation

  • Pregnancy category D
  • Transfer of Carbamazepine and its metabolite to breast milk

Precautions & Warnings

  • May cause dizziness and drowsiness
  • May cause skin reactions
  • May rarely cause liver problems
  • Decreases the blood levels of hormonal contraceptives
  • Effects on contraception
  • Gradual withdrawal advised
  • Caution in mixed seizures, elderly people, history of heart disease, kidney disease, liver disease, psychotic illness, raised pressure in the eye, history of blood disorders, history of previous Carmapine therapy

Therapeutic Class

  • Primary anti-epileptic drugs

Storage Conditions

  • Keep below 30°C temperature
  • Away from light & moisture
  • Keep out of the reach of children

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