Carmapine 100 mg/5 ml (Oral Suspension)

100 ml bottle: ৳ 250.00

Medicine Details

Category Details
Generic Carbamazepine
Company Incepta pharmaceuticals ltd
Also available as
Carmapine 200 mg tablet Carmapine cr 200 mg tablet

Indications

  • Partial and secondary generalized tonic-clonic seizures
  • Primary generalized tonic-clonic seizures
  • Trigeminal neuralgia
  • Prophylaxis of bipolar disorder

Pharmacology

  • Depresses activity in the nucleus ventralis of the thalamus
  • Reduces synaptic propagation of excitatory impulses
  • Decreases summation of temporal stimulation leading to neural discharge
  • LImits influx of Na ions across cell membrane
  • Stimulates the release of antidiuretic hormone (ADH)

Dosage & Administration

  • Initial dosage for adults and children over 12 years of age
  • Dosage for children 12-15 years of age
  • Dosage for children 6-12 years of age
  • Dosage for children under 6 years of age
  • Combination therapy

Interaction

  • Interaction with oral contraceptives
  • Interaction with hepatic enzyme inducers

Contraindications

  • Problems with the electrical message pathways in the heart (atrioventricular block)
  • History of decreased blood cell production by the bone marrow (bone marrow depression)
  • Hereditary blood disorders called porphyrias
  • Allergy to tricyclic antidepressants
  • Recent use of monoamine-oxidase inhibitor antidepressant (MAOI)

Side Effects

  • Dizziness
  • Drowsiness
  • Ataxia
  • Dry mouth
  • Abdominal pain
  • Nausea
  • Vomiting
  • Leucopenia
  • Proteinuria
  • Bradycardia
  • Heart failure
  • Hypotension
  • Erythematous skin rash
  • Aplastic anemia
  • Increased sensitivity to the sun

Pregnancy & Lactation

  • Pregnancy category D
  • Transfer to breast milk

Precautions & Warnings

  • May cause dizziness and drowsiness
  • May cause skin reactions
  • May cause liver problems
  • Decreases blood levels of hormonal contraceptives
  • Need for gradual discontinuation
  • Caution in mixed seizures including absence seizures
  • Caution in elderly people
  • Caution in history of heart disease
  • Caution in history of kidney disease
  • Caution in history of liver disease
  • Caution in history of psychotic illness
  • Caution in raised pressure in the eye (intraocular pressure)
  • Caution in history of blood disorders caused by medication
  • Caution in history of previous Carmapine therapy with side effects or allergy

Therapeutic Class

  • Primary anti-epileptic drugs

Storage Conditions

  • Keep below 30°C temperature
  • Away from light & moisture
  • Keep out of the reach of children

Related Brands