Carmapine 100 mg/5 ml (Oral Suspension)
100 ml bottle: ৳ 250.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Carbamazepine |
| Company | Incepta pharmaceuticals ltd |
| Also available as |
Indications
- Partial and secondary generalized tonic-clonic seizures
- Primary generalized tonic-clonic seizures
- Trigeminal neuralgia
- Prophylaxis of bipolar disorder
Pharmacology
- Depresses activity in the nucleus ventralis of the thalamus
- Reduces synaptic propagation of excitatory impulses
- Decreases summation of temporal stimulation leading to neural discharge
- LImits influx of Na ions across cell membrane
- Stimulates the release of antidiuretic hormone (ADH)
Dosage & Administration
- Initial dosage for adults and children over 12 years of age
- Dosage for children 12-15 years of age
- Dosage for children 6-12 years of age
- Dosage for children under 6 years of age
- Combination therapy
Interaction
- Interaction with oral contraceptives
- Interaction with hepatic enzyme inducers
Contraindications
- Problems with the electrical message pathways in the heart (atrioventricular block)
- History of decreased blood cell production by the bone marrow (bone marrow depression)
- Hereditary blood disorders called porphyrias
- Allergy to tricyclic antidepressants
- Recent use of monoamine-oxidase inhibitor antidepressant (MAOI)
Side Effects
- Dizziness
- Drowsiness
- Ataxia
- Dry mouth
- Abdominal pain
- Nausea
- Vomiting
- Leucopenia
- Proteinuria
- Bradycardia
- Heart failure
- Hypotension
- Erythematous skin rash
- Aplastic anemia
- Increased sensitivity to the sun
Pregnancy & Lactation
- Pregnancy category D
- Transfer to breast milk
Precautions & Warnings
- May cause dizziness and drowsiness
- May cause skin reactions
- May cause liver problems
- Decreases blood levels of hormonal contraceptives
- Need for gradual discontinuation
- Caution in mixed seizures including absence seizures
- Caution in elderly people
- Caution in history of heart disease
- Caution in history of kidney disease
- Caution in history of liver disease
- Caution in history of psychotic illness
- Caution in raised pressure in the eye (intraocular pressure)
- Caution in history of blood disorders caused by medication
- Caution in history of previous Carmapine therapy with side effects or allergy
Therapeutic Class
- Primary anti-epileptic drugs
Storage Conditions
- Keep below 30°C temperature
- Away from light & moisture
- Keep out of the reach of children