Carmapine CR 200 mg (Tablet (Controlled Release))

Unit Price: ৳ 5.00 (5 x 10: ৳ 250.00)
Strip Price: ৳ 50.00

Medicine Details

Category Details
Generic Carbamazepine
Company Incepta pharmaceuticals ltd
Also available as
Carmapine 200 mg tablet Carmapine 100 mg suspension

Indications

  • Partial and secondary generalized tonic-clonic seizures
  • Primary generalized tonic-clonic seizures
  • Trigeminal neuralgia
  • Prophylaxis of bipolar disorder

Pharmacology

  • Depresses activity in the nucleus ventralis of the thalamus
  • Reduces synaptic propagation of excitatory impulses
  • Decreases summation of temporal stimulation
  • Limits influx of Na ions across cell membrane
  • Stimulates the release of antidiuretic hormone (ADH)

Dosage & Administration

  • Initial dosage for adults and children over 12 years of age
  • Increase dosage at weekly intervals
  • Combination therapy guidelines
  • Initial and maintenance dosage for children of different age groups with epilepsy
  • Initial and maintenance dosage for trigeminal neuralgia

Interaction

  • Potential interaction with oral contraceptives
  • Hepatic enzyme inducers may increase metabolism
  • Possible increase in dosage required

Contraindications

  • Allergy to any ingredients
  • Atrioventricular block
  • History of bone marrow depression
  • Porphyrias
  • Allergy to tricyclic antidepressants
  • Recent use of monoamine oxidase inhibitor antidepressants

Side Effects

  • Common side effects
  • Severe adverse reactions in the hemopoietic system, skin, and cardiovascular system
  • Increased sensitivity to the sun
  • Use of sunscreen or protective clothing recommended

Pregnancy & Lactation

  • Pregnancy category D
  • Transfer of the medication to breast milk
  • Consideration for nursing or discontinuation of the drug

Precautions & Warnings

  • Potential dizziness and drowsiness
  • Special care during hazardous activities
  • Possible skin reactions and need for immediate medical assistance
  • Rare occurrence of liver problems
  • Impact on blood levels of hormonal contraceptives
  • Recommendation for gradual discontinuation
  • Caution in various medical conditions

Therapeutic Class

  • Primary anti-epileptic drugs

Storage Conditions

  • Recommended temperature and storage guidelines

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