Cefamax DS 180 mg/5 ml (Powder for Suspension)

60 ml bottle: ৳ 800.00

Medicine Details

Category Details
Generic Ceftibuten dihydrate
Company Incepta pharmaceuticals ltd
Also available as
Cefamax 400 mg capsule Cefamax 90 mg suspension Cefamax 200 mg capsule

Indications

  • Acute Bacterial Exacerbations of Chronic Bronchitis
  • Acute Bacterial Otitis Media
  • Pharyngitis and Tonsillitis

Pharmacology

Bactericidal action by binding to essential target proteins of the bacterial cell wall

Dosage & Administration

  • Otitis Media-Adult Dosage: 400 mg orally every 24 hours for 10 days
  • Tonsillitis/Pharyngitis-Adult Dosage: 400 mg orally every 24 hours for 10 days
  • Bronchitis-Adult Dosage: 400 mg orally every 24 hours for 10 days
  • Cystitis-Adult Dosage: 400 mg orally every 24 hours for 7 days
  • Pneumonia-Adult Dosage: 200 mg orally every 12 hours for 7 to 14 days
  • Sinusitis-Adult Dosage: 400 mg orally every 24 hours for 10 to 14 days
  • Urinary tract Infection-Adult Dosage: 400 mg orally every 24 hours for 10 days

Interaction

  • Theophylline & Antacid do not alter the pharmacokinetic profile of Cefamax DS
  • Ranitidine increases the Cmax & AUC of Cefamax DS

Contraindications

Known allergy to the cephalosporin group of antibiotics

Side Effects

  • Nausea
  • Headache
  • Diarrhea
  • Dyspepsia
  • Dizziness
  • Abdominal pain
  • Vomiting

Pregnancy & Lactation

Pregnancy Category B. Caution for nursing women

Precautions & Warnings

Possible emergence and overgrowth of resistant organisms. Dose adjustment in patients with varying degrees of renal insufficiency. Caution in individuals with a history of gastrointestinal disease

Use in Special Populations

  • Renal Impairment:
    • CrCl 5 to 29 ml/min: 2.25 mg/kg or 100 mg orally once a day
    • CrCl 30 to 49 ml/min: 4.5 mg/kg or 200 mg orally once a day
  • Hepatic Impairment: Dose adjustment not necessary

Therapeutic Class

Third generation Cephalosporins

Reconstitution

  • Pour the purified water completely into large bottle
  • Tighten the cap of large bottle and shake the bottle for at least one minute
  • Prepared suspension to be consumed within 14 days of preparation if kept in a refrigerator

Storage Conditions

Store below 25°C, protected from light and moisture. For Suspension: After reconstitution, the suspension may be used for 14 days while stored at 2° to 8°C. Keep out of reach of children

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