Synamet 100 mg+25 mg (Tablet)
Unit Price: ৳ 8.00 (3 x 10: ৳ 240.00)
Strip Price: ৳ 80.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Levodopa carbidopa fc tablet |
| Company | Healthcare pharmaceuticals ltd |
| Also available as |
Indications
- Treatment of Parkinson's disease
- Relief of parkinsonism symptoms
- Management of tremor
- Management of dysphagia
- Management of sialorrhea
- Management of postural instability
Description
- Levodopa acts as dopamine precursor
- Carbidopa inhibits DDC, increasing Levodopa availability in brain
Dosage & Administration
- Initial dosage of 100/10 mg tablet
- Initial dosage of 250/25 mg tablet
- Dosage titration based on patient response
- Individualized maintenance dose
- Limitation of total daily Carbidopa dosage
Interaction
- Potential postural hypotension with antihypertensives
- Reduced bioavailability with ferrous sulphate
- Reversal of therapeutic effects by phenytoin
- Severe orthostatic hypotension with selegiline
Contraindications
- Hypersensitivity to Carbidopa or Levodopa
- Narrow-angle glaucoma
- Suspicious undiagnosed skin lesions or history of melanoma
Side Effects
- Dyskinesias
- Nausea
- Syncope
- Chest pain
- Anorexia
- Palpitation
- Orthostatic effects
- Hypotensive episodes
- Hypertension
- Vomiting
- Gastrointestinal bleeding
- Dyspnea
- Alopecia
- Rash
- Dark urine
Pregnancy & Lactation
- Unknown effects on human pregnancy
- Potential hazards in women of childbearing potential
- Unknown excretion in human milk
Precautions & Warnings
- Not recommended for medicine-induced extrapyramidal reactions
- Caution in patients with severe cardiovascular or pulmonary disease
- Cautious administration in patients with wide-angle glaucoma
Use in Special Populations
- Not recommended for use in patients below the age of 18 years
Therapeutic Class
- Antiparkinson drugs
Storage Conditions
- Cool and dry place
- Protected from light