Oxagon 100 mcg/ml (IV Injection)

1 ml ampoule: ৳ 150.00

Medicine Details

Category Details
Generic Carbetocin
Company Healthcare pharmaceuticals ltd

Indications

  • Prevention of uterine atony
  • Prevention of postpartum hemorrhage
  • For use following caesarean section under epidural or spinal anesthesia

Pharmacology

  • Analog of oxytocin
  • Causes contraction of the uterus
  • Binds to oxytocin receptors
  • Increases uterine tone

Dosage & Administration

  • Single intravenous dose of 100 mcg
  • Administered by bolus injection
  • To be used as a single dose only

Interaction

  • No specific reported drug interactions

Contraindications

  • Not to be administered prior to delivery of the infant
  • Not for use in elective or medical induction of labor
  • Not for use in patients with hypersensitivity to oxytocin or carbetocin
  • Not for use in patients with cardiovascular diseases
  • Not intended for use in children

Side Effects

  • Nausea
  • Vomiting
  • Abdominal pain
  • Itching skin
  • Increased body temperature
  • Trembling
  • Weakness
  • Back pain
  • Dizziness
  • Metallic taste
  • Anaemia
  • Sweating
  • Chest pain
  • Dyspnoea
  • Chills
  • Tachycardia
  • Anxiety

Pregnancy & Lactation

  • Contraindicated during pregnancy
  • Small amount may cross into breast milk of nursing women
  • Not expected to present significant safety concern for nursing infants

Precautions & Warnings

  • Inadequate uterine contraction may require additional doses of oxytocin or ergometrine
  • May cause hyponatremia
  • Cautious use in epilepsy, migraine, asthma patients
  • Monitoring for changes in blood pressure in eclampsia and pre-eclampsia patients
  • Not recommended for elderly patients

Overdose Effects

  • Enhanced pharmacological effects associated with uterine hyperactivity and pain
  • Treatment consists of symptomatic and supportive management

Therapeutic Class

  • Drugs acting on the Uterus

Storage Conditions

  • Store at 2-8°C
  • Do not freeze
  • Keep away from light
  • Use immediately once ampoule is opened

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