Rotagan 200 mg (Tablet)

Unit Price: ৳ 200.00 (2 x 10: ৳ 4,000.00)
Strip Price: ৳ 2,000.00

Medicine Details

Category Details
Generic Favipiravir
Company Concord pharmaceuticals ltd

Indications

  • Treatment of novel or re-emerging pandemic influenza virus infections

Description

  • Approved for manufacture and sale in Japan as an influenza antiviral
  • Selective inhibition of the RNA polymerase of the influenza virus
  • Believed to be effective in treating COVID-19
  • Production and distribution at the discretion of Japan’s Health, Labor, and Welfare Ministry

Pharmacology

  • Metabolized into favipiravir ribosyl triphosphate
  • Selective inhibition of RNA polymerase of the influenza virus
  • Effective against all types and sub-types of human influenza viruses in vitro

Dosage & Administration

  • Usual adult dosage is 1600 mg of Favipiravir administered orally twice daily on Day 1
  • Total treatment duration should be 5 days

Interaction

  • Decreased RBC production in animal studies
  • Increases in liver function parameters in animal studies
  • Toxicity information regarding Rotagan in humans not readily available

Contraindications

  • Contraindicated for pregnant women and women who may possibly be pregnant

Side Effects

  • Most common side effects are diarrhea and increase of blood uric acid levels

Pregnancy & Lactation

  • May cause delayed development or death of embryos during the early stage of pregnancy
  • Should not be given during pregnancy

Precautions & Warnings

  • Should not be given in pregnant women
  • Requirement of confirmation of non-pregnancy in women of childbearing potential before use
  • Thorough contraception measures from the start of the treatment to 7 days after the end of the treatment
  • Caution should be taken for hepatic and renal impaired patients or use as per the direction of registered Physician

Use in Special Populations

  • Approved only as an experimental drug
  • Still many studies needed about its efficacy and toxic reactions and use in children

Overdose Effects

  • Decreased RBC production in animal studies
  • Increases in liver function parameters in animal studies
  • Toxicity information regarding Rotagan in humans not readily available

Therapeutic Class

  • Antiviral drugs

Storage Conditions

  • Keep below 30°C temperature
  • Protected from light & moisture
  • Keep out of the reach of children

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