GTN SR 2.6 mg (Tablet (Sustained Release))

Unit Price: ৳ 5.00 (6 x 10: ৳ 300.00)
Strip Price: ৳ 50.00

Medicine Details

Category Details
Generic Nitroglycerin tablet
Company Eskayef pharmaceuticals ltd

Indications

  • Prophylaxis of angina pectoris

Pharmacology

  • Causes relaxation of vascular smooth muscle
  • Produces a vasodilator effect on peripheral arteries and veins

Dosage & Administration

  • Dosage should be adjusted according to individual patient response
  • Recommended dosage for adults is one 2.6 mg sustained release tablet or capsule in morning and evening
  • Should be taken on an empty stomach

Interaction

  • May increase antihypertensive properties of vasodilators, calcium antagonists, and beta-adrenergic blockers
  • Concomitant use with tricyclic antidepressants and alcohol may cause high blood pressure
  • May cause fall in blood pressure when used with phosphodiesterase type 5 (PDE5) inhibitors
  • Aspirin decreases clearance and enhances hemodynamic effects
  • May reduce the pharmacologic effects of heparin
  • Increases the bioavailability of dihydroergotamine

Contraindications

  • Known hypersensitivity to nitroglycerin or related compounds
  • Acute myocardial infarction
  • Marked anemia
  • Head trauma
  • Cerebral hemorrhage
  • Closed-angle glaucoma

Side Effects

  • Headache at the onset of treatment
  • Tachycardia
  • Postural hypotension
  • Syncope
  • Cyanosis
  • Methemoglobinemia

Pregnancy & Lactation

  • No evidence on safety during pregnancy and lactation
  • Should be administered to pregnant or nursing women only if essential

Precautions & Warnings

  • Use with caution in patients predisposed to closed-angle glaucoma
  • Abrupt discontinuation may lead to symptom exacerbation
  • Long-term treatment should be discontinued gradually
  • Particular attention required during early days of acute myocardial infarction

Overdose Effects

  • Peripheral vasodilation
  • Fall in blood pressure
  • Reflex tachycardia
  • Monitoring of cardiac function and supportive measures necessary

Therapeutic Class

  • Nitrates: Coronary vasodilators

Storage Conditions

  • Store in a cool and dry place
  • Keep away from light and heat
  • Keep out of the reach of children

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