Lamogin 2 mg (Dispersible Tablet)
Unit Price: ৳ 7.00 (3 x 10: ৳ 210.00)
Strip Price: ৳ 70.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Lamotrigine |
| Company | Incepta pharmaceuticals ltd |
| Also available as |
Title
- Lamogin
Categories
- Antiepileptic drug
- Phenyltriazine antiepileptic
- Bipolar disorder medication
Description
Lamogin is a phenyltriazine antiepileptic used to treat some types of epilepsy and bipolar disorder. It controls epileptic seizures by inhibiting voltage-sensitive sodium channels, thereby stabilizing neuronal membranes and consequently inhibiting presynaptic excitatory neurotransmitter release.
Indications
- Adjunctive therapy for epilepsy (patients aged 2 years and older)
- Monotherapy for epilepsy (patients aged 16 years and older)
- Treatment for bipolar disorder (patients aged 18 years and older)
Mode of Action
- Inhibition of voltage-sensitive sodium channels
- Stabilization of neuronal membranes
- Inhibition of presynaptic excitatory neurotransmitter release
Dosage and Administration
- Various dosing regimens based on age, concomitant medications, and condition (epilepsy or bipolar disorder)
- Maintenance doses for different patient groups
Interactions
- Increased concentrations with valproate
- Decreased concentrations with carbamazepine, phenytoin, phenobarbital, primidone, rifampin, and estrogen-containing oral contraceptives
- Decreased exposure with protease inhibitors lopinavir/ritonavir and atazanavir/ritonavir
Side Effects
- Dizziness
- Headache
- Diplopia
- Nausea
- Blurred vision
- Somnolence
- Pharyngitis
- Rash
- Vomiting
- Diarrhea
- Infection
- Fever
- Abdominal pain
- Tremor
Pregnancy and Lactation
- Pregnancy Category C
- Excretion in human milk
- Potential for serious adverse reactions in nursing infants
Precautions and Warnings
- Discontinue at the first sign of rash
- Monitor for blood dyscrasias
- Monitor for suicidal behavior and ideation
- Monitor for signs of aseptic meningitis
Use in Special Populations
- Safety and effectiveness in very young pediatric patients not demonstrated for epilepsy
- Safety and effectiveness in pediatric patients not established for bipolar disorder
Overdose Effects
- Ataxia
- Nystagmus
- Seizures
- Decreased level of consciousness
- Coma
- Intraventricular conduction delay
Therapeutic Class
- Primary antiepileptic drugs
Storage Conditions
- Keep out of reach of children
- Store in a dry place
- Store below 25°C
- Protect from light