Mefoglip 2.5 mg+250 mg (Tablet)

Unit Price: ৳ 1.90 (5 x 10: ৳ 95.00)
Strip Price: ৳ 19.00

Medicine Details

Title

Glipizide & Metformin Tablet

Categories

  • Medication
  • Diabetes Management
  • Oral Hypoglycemic Preparations

Description

Glipizide & Metformin tablets are indicated for improving glycemic control in patients with type 2 diabetes. It contains two active ingredients, Glipizide and Metformin, which work in combination to help manage blood sugar levels.

Indications

  • Management of type 2 diabetes
  • Adjunct to diet and exercise
  • Initial therapy for hyperglycemia

Pharmacology

  • Metformin decreases hepatic glucose production
  • Glipizide stimulates insulin release from the pancreas
  • Improves insulin sensitivity

Dosage & Administration

  • To be taken once or twice daily with meals
  • Initiate at low dose with gradual escalation
  • Different starting doses for initial and second-line therapy

Interaction

  • Cimetidine reduces renal clearance of Metformin
  • Alcohol potentiates the effect of Metformin
  • Enhanced absorption with Nifedipine
  • Potentiation of sulfonylureas by certain drugs

Contraindications

  • Hypersensitivity to the drug
  • Renal impairment
  • Diabetic coma and ketoacidosis
  • Congestive heart failure
  • Pregnancy and breastfeeding

Side Effects

  • Hypoglycemia
  • Diarrhea
  • Nausea/vomiting
  • Abdominal pain
  • Headache
  • Musculoskeletal pain

Pregnancy & Lactation

  • Contraindicated during Pregnancy & Lactation

Precautions & Warnings

  • Metformin excretion by the kidney
  • Risk of Metformin accumulation and lactic acidosis in renal impairment
  • Careful titration in advanced age
  • Suspended use during surgical procedures
  • Monitoring blood glucose during sulfonylurea therapy

Therapeutic Class

  • Combination Oral hypoglycemic preparations

Storage Conditions

Store below 25°C in a cool and dry place.

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