Mefoglip DS 5 mg+500 mg (Tablet)

Unit Price: ৳ 3.70 (3 x 10: ৳ 111.00)

Strip Price: ৳ 37.00

Medicine Details

Category	Details
Generic	Glipizide metformin hydrochloride
Company	Incepta pharmaceuticals ltd
Also available as	Mefoglip 25 mg tablet Mefoglip 25 mg tablet

Indications

Initial therapy for type 2 diabetes
Adjunct to diet and exercise
Improves glycemic control

Pharmacology

Metformin decreases hepatic glucose production
Metformin improves insulin sensitivity
Glipizide stimulates insulin release from the pancreas

Dosage & Administration

Given once or twice daily with meals
Initiated at a low dose with gradual escalation
Recommended starting doses

Interaction

Cimetidine reduces renal clearance of Metformin
Alcohol potentiates the effects of Metformin
Hypoglycemic action of sulfonylureas may be potentiated by certain drugs

Contraindications

Hypersensitivity to the drug
Renal impairment
Diabetic coma and ketoacidosis
Chronic renal diseases
Congestive heart failure
Trauma
Dehydration
Alcohol dependence
Pregnancy
Breastfeeding

Side Effects

Hypoglycemia
Diarrhea
Nausea/vomiting
Abdominal pain
Headache
Musculoskeletal pain

Pregnancy & Lactation

Contraindicated during Pregnancy & Lactation

Precautions & Warnings

Metformin excretion by the kidney
Risk of Metformin accumulation and lactic acidosis
Titration of Metformin in advanced age
Metformin therapy during surgical procedure
Blood glucose monitoring during concomitant therapy with sulfonylurea

Therapeutic Class

Combination Oral hypoglycemic preparations

Storage Conditions

Store below 25°C in a cool and dry place

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