Chir DS 400 mg (Chewable Tablet)

Unit Price: ৳ 5.14 (10's pack: ৳ 51.40)

Medicine Details

Category Details
Generic Albendazole
Company Reliance pharmaceuticals ltd

Indications

  • Single and mixed infestations of hookworm, roundworm, threadworm, whipworm, strongyloides, tapeworm, opisthorchi, hydatid

Description

  • Benzimidazole anthelmintic
  • Active against nematodes and cestodes
  • Vermicidal, ovicidal, and larvicidal activity
  • Inhibitory effect on tubulin polymerization

Pharmacology

  • Broad spectrum anthelmintic
  • Blocks glucose uptake in helminths
  • Depletes energy level of helminths
  • Exerts anthelmintic effect by binding and inhibiting parasite tubulin polymerization
  • Extensively metabolized, probably in the liver

Dosage & Administration

  • Recommended doses for different types of infestations
  • Different dosages for adults, children (over 2 years, 1-2 years, under 1 year), and patients with hydatid disease
  • Treatment duration for cystic echinococcosis and alveolar echinococcosis

Interaction

  • No reported pharmacodynamic or pharmacokinetic interactions

Contraindications

  • Not normally used in neonates
  • Dosage reduction may be indicated in children weighing less than 10 kg
  • Not recommended during pregnancy or for women thought to be pregnant
  • No evidence to suggest dose alteration in renal, hepatic, or cardiac failure

Side Effects

  • Gastrointestinal disturbances
  • Headache
  • Dizziness
  • Changes in liver enzymes
  • Rarely reversible alopecia
  • Rash
  • Fever
  • Blood disorders including leucopenia and pancytopenia
  • Allergic shock if cyst leakage
  • Convulsion and meningism in cerebral disease

Pregnancy & Lactation

  • US FDA Pregnancy category C
  • Avoided in pregnancy and lactation unless benefits outweigh risks

Precautions & Warnings

  • Blood counts and liver function tests before treatment and twice during each cycle
  • Breastfeeding
  • Exclude pregnancy before starting treatment
  • Constant medical supervision with regular monitoring for Echinococcosis treatment

Therapeutic Class

  • Anthelmintic

Storage Conditions

  • Keep in a dry place
  • Away from light and heat
  • Keep out of the reach of children

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