Chir DS 400 mg (Chewable Tablet)
Unit Price: ৳ 5.14 (10's pack: ৳ 51.40)
Medicine Details
Category | Details |
---|---|
Generic | Albendazole |
Company | Reliance pharmaceuticals ltd |
Indications
- Single and mixed infestations of hookworm, roundworm, threadworm, whipworm, strongyloides, tapeworm, opisthorchi, hydatid
Description
- Benzimidazole anthelmintic
- Active against nematodes and cestodes
- Vermicidal, ovicidal, and larvicidal activity
- Inhibitory effect on tubulin polymerization
Pharmacology
- Broad spectrum anthelmintic
- Blocks glucose uptake in helminths
- Depletes energy level of helminths
- Exerts anthelmintic effect by binding and inhibiting parasite tubulin polymerization
- Extensively metabolized, probably in the liver
Dosage & Administration
- Recommended doses for different types of infestations
- Different dosages for adults, children (over 2 years, 1-2 years, under 1 year), and patients with hydatid disease
- Treatment duration for cystic echinococcosis and alveolar echinococcosis
Interaction
- No reported pharmacodynamic or pharmacokinetic interactions
Contraindications
- Not normally used in neonates
- Dosage reduction may be indicated in children weighing less than 10 kg
- Not recommended during pregnancy or for women thought to be pregnant
- No evidence to suggest dose alteration in renal, hepatic, or cardiac failure
Side Effects
- Gastrointestinal disturbances
- Headache
- Dizziness
- Changes in liver enzymes
- Rarely reversible alopecia
- Rash
- Fever
- Blood disorders including leucopenia and pancytopenia
- Allergic shock if cyst leakage
- Convulsion and meningism in cerebral disease
Pregnancy & Lactation
- US FDA Pregnancy category C
- Avoided in pregnancy and lactation unless benefits outweigh risks
Precautions & Warnings
- Blood counts and liver function tests before treatment and twice during each cycle
- Breastfeeding
- Exclude pregnancy before starting treatment
- Constant medical supervision with regular monitoring for Echinococcosis treatment
Therapeutic Class
- Anthelmintic
Storage Conditions
- Keep in a dry place
- Away from light and heat
- Keep out of the reach of children