Telsan 40 mg (Tablet)
Unit Price: ৳ 10.00 (3 x 10: ৳ 300.00)
Strip Price: ৳ 100.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Telmisartan |
| Company | Orion pharma ltd |
Indications
- Treatment of essential hypertension in adults
- Reduction of cardiovascular morbidity in adults with atherothrombotic cardiovascular disease or type 2 diabetes mellitus with documented organ damage
Pharmacology
- Non-peptide angiotensin-II receptor antagonist
- Blocks vasoconstrictor and aldosterone secreting effects of angiotensin-II
- Independent of pathways for angiotensin-II synthesis
- Does not inhibit ACE
- Does not affect the response to bradykinin
- Does not bind to or block other hormone receptors or ion channels known to be important in cardiovascular regulation
Dosage & Administration
- Usual starting dose of 40 mg once a day
- Blood pressure response is dose-related (20 to 80 mg)
- Most antihypertensive effect apparent within 2 weeks
- May be administered with other antihypertensive agents
- May be administered with or without food
- Not recommended for patients ≥75 years old or with hepatic impairment
- Pediatric use safety and effectiveness not established
- No initial dosage adjustment necessary for elderly patients or patients with renal impairment
- Monitor carefully and up titrate slowly in patients with biliary obstructive disorders or hepatic insufficiency
Interaction
- Increased risk of renal impairment and loss of antihypertensive effect with NSAIDs
- Co-administration with aliskiren should be avoided in patients with diabetes
Contraindications
- Known hypersensitivity to the product or any of its components
Side Effects
- Common side effects include sinus pain and congestion, back pain, diarrhea (hypertensive patients)
- Common side effects include intermittent claudication and skin ulcer (patients of cardiovascular risk reduction)
Pregnancy & Lactation
- Pregnancy Category C (first trimester) and D (second and third trimester)
- Potential adverse effects on the nursing infant
- Consider discontinuing nursing or drug, taking into account the importance of the drug to the mother
Precautions & Warnings
- Avoid fetal or neonatal exposure
- Hypotension
- Monitor carefully in patients with impaired hepatic or renal function
- Avoid concomitant use of an ACE inhibitor and angiotensin receptor blocker
Overdose Effects
- Likely manifestations include hypotension, dizziness, tachycardia, bradycardia, increase in serum creatinine, and acute renal failure
Therapeutic Class
- Angiotensin-II receptor blocker
Storage Conditions
- Do not store above 30°C
- Protect from light and high humidity
- Keep out of the reach of children