Taglimet 50 mg+1000 mg (Tablet)

Unit Price: ৳ 11.00 (3 x 10: ৳ 330.00)

Strip Price: ৳ 110.00

Medicine Details

Category	Details
Generic	Sitagliptin metformin hydrochloride
Company	Ibn sina pharmaceuticals ltd
Also available as	Taglimet 50 mg tablet

Indications

Adjunct to diet and exercise for type 2 diabetes mellitus
Improves glycemic control in adults

Pharmacology

Combines sitagliptin and metformin
Mechanism of action for both agents
Incretin hormone involvement
Physiological regulation of glucose homeostasis

Dosage & Administration

Individualized dosage
Maximum recommended daily dose
Twice daily with meals
Gradual dose escalation
Initial combination therapy
Dose adjustment for patients already on metformin
Extended-release tablet administration
Co-administration with insulin
Monitoring during therapy change

Interaction

Cationic drugs caution
Interaction with phenprocoumon
Interaction with levothyroxine

Contraindications

Renal disease or dysfunction
Metabolic acidosis
Hypersensitivity reaction history
Radiologic studies contraindication

Side Effects

Common adverse reactions
Adverse reactions with different combination therapies
Adverse reactions due to metformin initiation

Pregnancy & Lactation

Pregnancy category B
Lactation caution

Precautions & Warnings

Risk of lactic acidosis
Monitoring TSH levels in hypothyroidism
Monitoring vitamin B12 levels
Hepatic disease caution
Renal function assessment
Acute pancreatitis warning
Hematologic parameter monitoring
Alcohol intake caution
Insulin use during stress
Allergic and hypersensitivity reactions caution
No conclusive evidence of macrovascular risk reduction

Overdose Effects

Sitagliptin overdose measures
Modestly dialyzable sitagliptin
Metformin overdose measures
Dialyzable metformin
Pancreatitis risk

Therapeutic Class

Combination oral hypoglycemic preparations

Storage Conditions

Storage below 25°C
Dry place away from light
Safe place out of reach of children
Dispense on prescription only

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