Taglimet 50 mg+500 mg (Tablet)
Unit Price: ৳ 9.00 (3 x 10: ৳ 270.00)
Strip Price: ৳ 90.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Sitagliptin metformin hydrochloride |
| Company | Ibn sina pharmaceuticals ltd |
| Also available as |
Indications
- Adjunct to diet and exercise for type 2 diabetes mellitus
- Not for use in type 1 diabetes or diabetic ketoacidosis
- Unknown risk in patients with history of pancreatitis
Pharmacology
- Combines sitagliptin and metformin for glycemic control
- Sitagliptin is a DPP-4 inhibitor
- Metformin decreases hepatic glucose production
Dosage & Administration
- Individualized dosage based on patient's regimen
- Maximum recommended daily dose of 100mg sitagliptin and 2000mg metformin
- Twice daily administration with meals
Interaction
- Use caution with cationic drugs eliminated by renal tubular secretion
- Monitoring recommended for phenprocoumon and levothyroxine
Contraindications
- Renal disease or dysfunction
- Acute or chronic metabolic acidosis
- History of serious hypersensitivity reaction
Side Effects
- Common adverse reactions like diarrhea, upper respiratory tract infection, headache
- Hypoglycemia in combination with insulin
- Gastrointestinal adverse reactions due to metformin initiation
Pregnancy & Lactation
- Pregnancy Category B
- Caution advised during lactation
Precautions & Warnings
- Risk of lactic acidosis
- Monitoring recommended for hypothyroidism and vitamin B12 levels
- Postmarketing reports of acute renal failure and pancreatitis
- Annual monitoring of hematologic parameters
- Caution against excessive alcohol intake
Overdose Effects
- Supportive measures for sitagliptin overdose
- Dialyzable characteristics of metformin in overdose
Therapeutic Class
- Combination oral hypoglycemic preparations
Storage Conditions
- Store below 25°C in a dry place away from light
- Keep out of reach of children
- Dispense only on prescription