Bisopol 2.5 mg (Tablet)

Unit Price: ৳ 5.00 (5 x 10: ৳ 250.00)
Strip Price: ৳ 50.00

Medicine Details

Category Details
Generic Bisoprolol hemifumarate
Company Euro pharma ltd
Also available as
Bisopol 5 mg tablet

Indications

  • Hypertension
  • Angina
  • Moderate to severe heart failure

Pharmacology

  • Selective ß1 blocker
  • Reduces heart rate and cardiac output
  • Decreases arterial hypertension
  • High affinity for ß1 receptor
  • Lipid metabolism impact
  • Absolute bioavailability of 88%
  • Extensively distributed
  • Metabolized via oxidative pathways
  • Primarily metabolized via CYPSA4
  • Balanced clearance between renal elimination and hepatic metabolism
  • Elimination half-life of 10-12 hours

Dosage & Administration

  • Starting dose of 5 mg once daily
  • Dose may be increased to 10 mg and then to 20 mg once daily
  • Appropriate interval for dose titration is 2 weeks
  • Safety and effectiveness not established in children
  • Initial daily dose should be 5 mg in patients with hepatic or renal impairment
  • Dose adjustment caution in patients with impaired renal or hepatic function

Interaction

  • Avoid combination with other β-blocking agents
  • Monitor patients receiving catecholamine-depleting drugs
  • Care when used with centrally active antihypertensive agents
  • Use with caution when myocardial depressants or inhibitors of A-V conduction are used concurrently
  • Combined use with calcium channel blockers can lead to severe hypotension and cardiac failure

Contraindications

  • Cardiogenic shock
  • Overt heart failure
  • Second or third degree A-V block
  • Right ventricular failure secondary to pulmonary hypertension
  • Sinus bradycardia

Side Effects

  • Fatigue
  • Dizziness
  • Headache
  • Disturbances of the gut
  • Cold or numb extremities
  • Muscle weakness or cramps
  • Breathing difficulties due to bronchospasm
  • Nausea
  • Vomiting
  • Diarrhea
  • Constipation
  • Abdominal pain

Pregnancy & Lactation

  • Potential fetal risk justifies potential benefit
  • No studies in pregnant women
  • Consideration in lactating mothers

Precautions & Warnings

  • Use caution in adjusting the dose in patients with impaired renal or hepatic function
  • Patients with severe anaphylactic reaction history may be more reactive to allergens
  • Unresponsive to usual doses of epinephrine used to treat allergic reactions

Therapeutic Class

  • Anti adrenergic agent (Beta blockers)

Storage Conditions

  • Keep in a dry place
  • Away from light and heat
  • Keep out of the reach of children

Chemical Structure

  • Molecular Formula: C18H31NO4

Common Questions about Bisopol 2.5 mg Tablet

  • Heart rate-regulating medication
  • Used for high blood pressure, chest pain, and heart failure
  • Oral administration once daily, with or without food
  • Side effects include dizziness, fatigue, headache, slow heart rate, difficulty breathing, and cold extremities
  • Generally safe, but consult a doctor with health conditions
  • Requires intake after food in prescribed dosage
  • Store in a cool, dry place in original packaging

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