Singlin 1 mg (Tablet)
Unit Price: ৳ 3.00 (10 x 10: ৳ 300.00)
Strip Price: ৳ 30.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Repaglinide |
| Company | Renata limited |
| Also available as |
Indications
- Adjunct to diet and exercise for type 2 diabetes mellitus
- Lowering blood glucose levels
Description
- Oral blood-glucose-lowering drug of the meglitinide class
- Management of Type 2 diabetes mellitus (NIDDM)
- Stimulates insulin secretion
Pharmacology
- Binds to specific receptors leading to closure of K+ channels
- Leads to Ca++ influx and insulin secretion
Dosage & Administration
- Starting dose based on HbA1c level
- Taken before each meal
- Dosage adjustment at intervals
- Maximum 16 mg daily
Interaction
- Potential interactions with cytochrome P450 inhibitors and inducers
- Effects on drugs like Cimetidine, Digoxin, NSAIDs, and others
Contraindications
- Diabetic ketoacidosis
- Type 1 diabetes mellitus
- Known hypersensitivity to the drug or its inactive ingredients
Side Effects
- Hypoglycemia and related symptoms
- Upper respiratory tract infections
- Diarrhea, constipation, nausea, vomiting
- Hypersensitivity reactions like rashes and urticaria
Pregnancy & Lactation
- Safety in pregnant women not established
- Use during pregnancy only if clearly needed
- Unknown excretion in human milk
Precautions & Warnings
- Substitution with insulin during concurrent illness and surgery
- Risks of hypoglycemia
Overdose Effects
- Few adverse effects at high doses
- Hypoglycemia with severe reactions infrequently
Therapeutic Class
- Meglitinide Analogues
Storage Conditions
- Do not store above 30°C
- Keep away from light and out of the reach of children