Fluconazole 50 mg (Capsule)
Unit Price: ৳ 7.00 (3 x 10: ৳ 210.00)
Strip Price: ৳ 70.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Fluconazole |
| Company | Biogen pharmaceuticals ltd |
| Also available as |
Indications
- Vaginal Candidiasis
- Oropharyngeal Candidiasis
- Oesophageal Candidiasis
- Tinea corporis/Tinea cruris/Tinea pedis/Other Tinea
- Kerion
- Pityriasis versicolor
- Onychomycosis
- Invasive candidal infections and cryptococcal infections (including meningitis)
- Prevention of cryptococcal meningitis
- Prevention of fungal infections in immunocompromised patients
- Systemic Candidiasis and Cryptococcal infection
- Fungal urinary tract infections
- Disseminated candidiasis
- Prophylaxis for fungal infection in neutropenic cancer patients
- Acute treatment of other systemic fungal infections such as coccidioidomycosis and histoplasmosis
Pharmacology
Triazole antifungal agent, potent inhibitor of fungal cytochrome P-450 dependent enzymes
Dosage & Administration
- Various dosage regimens for different indications in adults and children
- Dosage adjustments for elderly patients and those with renal impairment
Interaction
- Interaction with warfarin, sulphonyl ureas, hydrochlorothiazide, phenytoin, rifampicin, oral contraceptives, cyclosporin, food, cimetidine, antacids, theophylline
- Monitoring and potential dose adjustments for theophylline and cyclosporin levels
Contraindications
Hypersensitivity to Fluconazole or related triazole compounds
Side Effects
- Common gastrointestinal symptoms
- Rarely encountered adverse events such as rash and anaphylaxis
Pregnancy & Lactation
Adverse fetal effects seen in animals at high maternal dose levels, not recommended in pregnancy or in women of childbearing potential without adequate contraception
Precautions & Warnings
- Abnormalities in hepatic, renal, haematological, and biochemical function tests in some patients
- Rare occurrences of hepatic necrosis, exfoliative cutaneous reactions, and severe cutaneous reactions especially in AIDS patients
- Use of fluconazole not recommended during lactation
Use in Special Populations
- Normal dose in elderly (no evidence of renal impairment)
- Dosage adjustments in renal impairment based on creatinine clearance
- No adjustments in single dose therapy for renal impairment
Overdose Effects
Supportive and symptomatic treatment, forced volume diuresis may increase elimination rate, haemodialysis decreases plasma levels by approximately 50%
Therapeutic Class
Drugs for subcutaneous and mycoses
Storage Conditions
Keep in a dry place away from light and heat, keep out of the reach of children