L-Amlo 1.25 mg (Tablet)

Unit Price: ৳ 4.00 (3 x 10: ৳ 120.00)
Strip Price: ৳ 40.00

Medicine Details

Indications

  • Treatment of hypertension
  • Lowering blood pressure
  • Reducing risk of cardiovascular events

Pharmacology

  • Calcium channel blocker
  • Inhibits transmembrane influx of calcium ions
  • Pharmacologically active isomer
  • Absorption unaffected by food
  • Metabolized by CYP3A4
  • 60% eliminated in urine

Dosage & Administration

  • Oral route of administration
  • Initial dose of 2.5 mg once daily
  • Maximum dose of 5 mg once daily
  • Dosage adjustment for elderly and hepatic insufficiency patients
  • Effective dose for pediatric patients 6-17 years

Interaction

  • Impact of CYP3A Inhibitors on amlodipine
  • Impact of amlodipine on Simvastatin and Immunosuppressants
  • Can be taken with or without food
  • Avoid grapefruit products & natural licorice

Contraindications

  • Contraindicated in patients with known sensitivity to amlodipine

Side Effects

  • Common: Difficulty in breathing, Dizziness, Reflex Tachycardia, Hypotension, Abdominal Pain & Edema
  • Rare: Diarrhea, Back pain, Headache, Fatigue & Nausea

Pregnancy & Lactation

  • Limited data on amlodipine use in pregnant women
  • No adverse effects on breastfed infants observed

Precautions & Warnings

  • Possible symptomatic hypotension
  • Worsening angina or myocardial infarction
  • Titration for patients with hepatic failure

Overdose Effects

  • Marked hypotension and reflex tachycardia

Therapeutic Class

  • Calcium-channel blockers

Storage Conditions

  • Store in a cool & dry place
  • Protect from light & moisture
  • Keep out of reach of children

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