L-Amlo 5 mg (Tablet)
Unit Price: ৳ 9.00 (3 x 10: ৳ 270.00)
Strip Price: ৳ 90.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Levamlodipine maleate |
| Company | Navana pharmaceuticals ltd |
| Also available as | L amlo 125 mg tabletL amlo 25 mg tablet |
Indications
- Treatment of hypertension
- Lowering blood pressure
- Reducing risk of cardiovascular events
Pharmacology
- Dihydropyridine calcium antagonist
- Inhibits calcium ion influx into muscle cells
- Metabolism primarily mediated by CYP3A4
Dosage & Administration
- Oral administration
- Initial dose of 2.5 mg once daily
- Maximum dose of 5 mg once daily
- Titration needed for dosage adjustment
Interaction
- Impact of CYP3A Inhibitors on Amlodipine
- Impact of Amlodipine on other drugs like simvastatin and immunosuppressants
- Can be taken with or without food
- Avoid grapefruit products & natural licorice
Contraindications
- Contraindicated in patients with known sensitivity to amlodipine
Side Effects
- Common side effects include difficulty in breathing, dizziness, reflex tachycardia, hypotension, abdominal pain & edema
- Rare side effects include diarrhea, back pain, headache, fatigue & nausea
Pregnancy & Lactation
- Limited data available for pregnant women
- No adverse effects on the breastfed infant observed
Precautions & Warnings
- Symptomatic hypotension is possible
- Worsening angina and acute myocardial infarction can develop
- Titrate slowly in patients with severe hepatic impairment
Overdose Effects
- Excessive peripheral vasodilation with marked hypotension and reflex tachycardia
Therapeutic Class
- Calcium-channel blockers
Storage Conditions
- Store in a cool & dry place
- Protect from light & moisture
- Keep out of reach of children