Acifix 20 mg (Tablet (Enteric Coated))

Unit Price: ৳ 7.00 (10 x 10: ৳ 700.00)
Strip Price: ৳ 70.00

Medicine Details

Category Details
Generic Rabeprazole sodium
Company Beximco pharmaceuticals ltd
Also available as
Acifix 20 mg capsule

Title

  • Acifix Gastro-resistant tablets

Categories

  • Medicine
  • Gastrointestinal
  • Pharmaceutical

Indications

  • Treatment of active duodenal ulcer
  • Treatment of active benign gastric ulcer
  • Treatment of symptomatic erosive or ulcerative gastro-esophageal reflux disease (GERD)
  • Long-term management of gastro-esophageal reflux disease (GERD Maintenance)
  • Symptomatic treatment of moderate to very severe gastro-esophageal reflux disease (symptomatic GERD)
  • Treatment of Zollinger-Ellison Syndrome
  • Eradication of Helicobacter pylori in patients with peptic ulcer disease

Pharmacology

  • Inhibition of gastric proton-pump
  • Suppression of gastric acid secretion

Dosage

  • Recommended oral dose for active duodenal ulcer and active benign gastric ulcer: 20 mg once daily in the morning
  • Recommended oral dose for erosive or ulcerative gastro-esophageal reflux disease: 20 mg once daily for four to eight weeks
  • Maintenance dose of rabeprazole sodium 20 mg or 10 mg once daily
  • Dosage for treatment of GERD in pediatric patients

Administration

  • Tablets to be taken in the morning before eating

Interaction

  • Potential interaction with compounds dependent on gastric pH
  • Potential decrease in antifungal plasma levels when co-administered with ketoconazole or itraconazole
  • No interaction with liquid antacids
  • Not recommended to be co-administered with atazanavir

Contraindications

  • Hypersensitivity to the active substance or excipients
  • Contraindicated in pregnancy and during breastfeeding

Side Effects

  • Headache
  • Diarrhoea
  • Abdominal pain
  • Vomiting
  • Constipation
  • Dry mouth
  • Drowsiness
  • Dizziness
  • Increased or decreased appetite
  • Muscle pain

Pregnancy & Lactation

  • US FDA pregnancy category 'C'
  • No adequate and well-controlled studies in pregnant women
  • Likely excretion in human milk

Precautions & Warnings

  • Symptomatic response does not exclude the presence of malignancy
  • Regular surveillance for long-term treatment
  • Potential increase in risk of hip, wrist, and spine fracture
  • Risk of cross-hypersensitivity reactions
  • Reports of blood dyscrasias and hepatic enzyme abnormalities
  • Care advised for patients with severe hepatic dysfunction

Use in Special Populations

  • No dosage adjustment necessary for patients with renal or hepatic impairment
  • Not recommended for use in children

Overdose Effects

  • Maximum established exposure not exceeding 60 mg twice daily
  • Effects generally minimal and reversible without further medical intervention

Therapeutic Class

  • Proton Pump Inhibitor

Storage Conditions

  • Keep below 30°C temperature, away from light & moisture

Chemical Structure

  • Molecular formula: C18H21N3O3S

Common Questions

  • What is Acifix 20 mg Tablet?
  • What is Acifix 20 mg Tablet used for?
  • What are the side effects of Acifix 20 mg Tablet?
  • How should I take Acifix 20 mg Tablet?
  • Can I take Acifix 20 mg Tablet while pregnant or breastfeeding?
  • What should I do if I overdose on Acifix 20 mg Tablet?
  • How long should I take Acifix 20 mg Tablet?
  • Is there anything else I should know about Acifix 20 mg Tablet?
  • Does Acifix 20 mg Tablet cause bone problems?
  • Can I take Acifix 20 mg Tablet with vitamin D?

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