Motelity 2 mg (Tablet)
Unit Price: ৳ 24.00 (2 x 10: ৳ 480.00)
Strip Price: ৳ 240.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Prucalopride succinate |
| Company | Nuvista pharma ltd |
| Also available as |
Indications
- Symptomatic treatment of chronic constipation in adults
Pharmacology
- Stimulates motility by interacting specifically with 5-HT4 receptors in the GI tract
Dosage & Administration
- Adult dose: 2 mg once daily with or without food
- Older people: Start with 1 mg once daily; if needed the dose can be increased to 2 mg once daily
- Children: Not recommended for children and adolescents younger than 18 years
Interaction
- Low interaction potential with other medicinal products
- May have minor interaction with P-gp inhibitors like ketoconazole, verapamil, cyclosporine A, and quinidine
Contraindications
- Hypersensitivity to the active substance or to any of the excipients
- Renal impairment requiring dialysis
Side Effects
- Frequently reported adverse reactions: headache (17.8%) and gastrointestinal symptoms (abdominal pain), nausea, and diarrhea
Pregnancy & Lactation
- Not recommended during pregnancy
- Use effective contraception during treatment
- Not recommended during breastfeeding due to lack of human data
Precautions & Warnings
- Caution in severe hepatic impairment
- Possible reduction of efficacy of oral contraceptives in case of severe diarrhea
Use in Special Populations
- Dose adjustment for patients with severe renal impairment (GFR <30 ml/min/1.73 m2)
- Dose adjustment for patients with severe hepatic impairment (Child-Pugh class C)
Overdose Effects
- May result in symptoms like headache, nausea, and diarrhea
- Specific treatment is not available for overdose
- Symptomatic and supportive measures may be instituted
Therapeutic Class
- Osmotic purgatives
Storage Conditions
- Store at room temperature, below 30°C
- Do not remove desiccant
- Dispense in original bottle