Trizedon MR 35 mg (Tablet (Modified Release))

Unit Price: ৳ 8.00 (3 x 10: ৳ 240.00)
Strip Price: ৳ 80.00

Medicine Details

Category Details
Generic Trimetazidine dihydrochloride
Company Renata limited

Indications

  • Add-on therapy for stable angina pectoris
  • Symptomatic treatment for angina pectoris

Pharmacology

  • First 3-keto acyl CoA thiolase inhibitor
  • Metabolic anti-ischemic agent
  • Inhibition of fatty acid pathway
  • Transfer of oxygen to glucose pathway
  • Aerobic oxidation of glucose
  • Reduction of lactic acid production

Dosage & Administration

  • Recommended dose of 35mg twice daily
  • Recommended dose of 20mg thrice daily during meals
  • Assessment of treatment response after three months
  • Discontinuation of treatment if no response

Interaction

  • No reported drug interactions
  • No interactions with beta-blockers, calcium antagonists, nitrates, heparin, hypolipidemic agents or digitalis preparation

Contraindications

  • Hypersensitivity to the active substance or excipients
  • Parkinson's disease or parkinsonian symptoms
  • Tremors and restless legs movement disorders
  • Severe renal impairment

Side Effects

  • Common side effects: dizziness, headache, abdominal pain, diarrhea, dyspepsia, nausea, vomiting, rash, pruritus, urticaria, asthenia

Pregnancy & Lactation

  • No data on use in pregnant women
  • No direct or indirect harmful effects in animal studies
  • Preferable to avoid use during pregnancy
  • Unknown excretion in human milk
  • Risk cannot be excluded for newborns/infants
  • Not recommended during breast-feeding

Precautions & Warnings

  • Not a curative treatment for angina attacks
  • Not an initial treatment for unstable angina pectoris
  • Not a treatment for myocardial infarction

Therapeutic Class

  • Other Anti-anginal & Anti-ischaemic drugs

Storage Conditions

  • Keep in a dry place away from light and heat
  • Keep out of the reach of children

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