Pyrexil Extend 665 mg (Tablet (Extended Release))

Unit Price: ৳ 2.00 (10 x 10: ৳ 200.00)
Strip Price: ৳ 20.00

Medicine Details

Category Details
Generic Paracetamol
Company Veritas pharmaceuticals ltd

Title

Pyrexil Extend 665 mg Tablet

Categories

  • Medicine
  • Healthcare
  • Pharmaceuticals

Description

Pyrexil Extend is indicated for fever, common cold and influenza, headache, toothache, earache, bodyache, myalgia, neuralgia, dysmenorrhoea, sprains, colic pain, back pain, post-operative pain, postpartum pain, inflammatory pain, and post-vaccination pain in children. It is also indicated for rheumatic & osteoarthritic pain and stiffness of joints.

Indications

  • Fever relief
  • Cold relief
  • Influenza relief
  • Headache relief
  • Toothache relief
  • Earache relief
  • Myalgia relief
  • Neuralgia relief
  • Dysmenorrhoea relief
  • Sprains relief
  • Colic pain relief
  • Back pain relief
  • Post-operative pain relief
  • Postpartum pain relief
  • Inflammatory pain relief
  • Post-vaccination pain relief
  • Rheumatic pain relief
  • Osteoarthritic pain relief

Pharmacology

  • Properties:
    • Analgesic
    • Antipyretic
    • Weak anti-inflammatory activity
    • Acts in the CNS
    • Increases pain threshold
    • Inhibits COX-1, COX-2, and COX-3 enzymes
    • Involved in prostaglandin (PG) synthesis
  • ChemicalStructure: C8H9NO2

DosageAdministration

  • Tablet:
    • Adult: 1-2 tablets every 4 to 6 hours up to a maximum of 4 gm (8 tablets) daily
    • Children (6-12 years): ½ to 1 tablet 3 to 4 times daily
  • ExtendedReleaseTablet: Two tablets every 6 to 8 hours (max 6 tablets in 24 hours)
  • SyrupSuspension:
    • Children under 3 months: 10 mg/kg body weight 3 to 4 times daily
    • Adults: 4-8 teaspoonful 3 to 4 times daily
  • Suppository:
    • Children 3-12 months: 60-120 mg 4 times daily
    • Adults & children over 12 years: 0.5-1 gm 4 times daily

Interaction

Diminished ability with barbiturates, tricyclic antidepressants, and alcohol; increased hepatotoxicity with alcohol

Contraindications

Known hypersensitivity to Paracetamol

SideEffects

  • Mild side effects
  • Haematological reactions
  • Thrombocytopenia
  • Leucopenia
  • Pancytopenia
  • Neutropenia
  • Agranulocytosis
  • Pancreatitis
  • Skin rashes
  • Allergic reactions

PregnancyLactation

Epidemiological studies show no ill effects in human pregnancy; excreted in breast milk in non-clinically significant amount

PrecautionsWarnings

  • For patients with severe renal or severe hepatic impairment
  • Hazard of overdose greater in non-cirrhotic alcoholic liver disease
  • Not to exceed stated dose
  • Avoid concurrent use with other Pyrexil Extend-containing products

OverdoseEffects

  • Symptoms:
    • Pallor
    • Nausea
    • Vomiting
    • Abdominal pain
    • Liver damage
    • Abnormalities of glucose metabolism
    • Metabolic acidosis
    • Hepatic failure
    • Acute renal failure
  • Treatment:
    • Activated charcoal within 1 hour of overdose
    • Measurement of Plasma Pyrexil Extend concentration at 4 hours or later
    • Treatment with N-acetylcysteine within 24 hours
    • Intravenous N-acetylcysteine

TherapeuticClass

Non-opioid analgesics

StorageConditions

Dry place, away from light and heat, keep out of reach of children

ChemicalStructure

  • MolecularFormula: C8H9NO2
  • ChemicalStructureURL: https://medex.com.bd/storage/res/g-res-860-paracetamol-chemical-structure-JLKHDuG7hxR2MserFZ27.svg

CommonlyAskedQuestions

  • QuestionAnswers:
      • Question: What is Pyrexil Extend 665 mg XR Tablet?
      • Answer: Obstructs the release of pain and fever chemical messengers
      • Question: What are the uses of Pyrexil Extend 665 mg XR Tablet?
      • Answer: Treatment and prevention of conditions and symptoms of diseases
      • Question: What are the Side Effects of Pyrexil Extend 665 mg XR Tablet Pyrexil Extend 665 mg XR Tablet?
      • Answer: Allergic reaction, gastric ulcers, fatigue, anemia, nausea, vomiting
      • Question: What are the instructions for storage and disposal Pyrexil Extend 665 mg XR Tablet?
      • Answer: Stored at room temperature, away from heat and direct light, keep away from children and pets
      • Question: Should I use Pyrexil Extend 665 mg XR Tablet empty stomach, before food or after food?
      • Answer: With food or milk for better effectiveness
      • Question: How long do I need to use Pyrexil Extend 665 mg XR Tablet before I see improvement in my conditions?
      • Answer: Use until the complete eradication of the disease as directed by the doctor
      • Question: Is there any food or drink I need to avoid while taking Pyrexil Extend 665 mg XR Tablet?
      • Answer: Can follow normal diet under the usage of Pyrexil Extend 665 mg XR Tablet
      • Question: Will Pyrexil Extend 665 mg XR Tablet be more effective if taken in more than the recommended dose?
      • Answer: No need to take more than recommended doses
      • Question: Can I take other medications along with Pyrexil Extend 665 mg XR Tablet?
      • Answer: Do not use any OTC for cough, cold, allergy, or pain medication without consulting a doctor or pharmacist
      • Question: Can I take Pyrexil Extend 665 mg XR Tablet with antibiotics?
      • Answer: Ask your doctor or pharmacist if you can take Pyrexil Extend 665 mg XR Tablet at the same time as antibiotics
      • Question: Is Pyrexil Extend 665 mg XR Tablet an NSAID drug?
      • Answer: Not classified as an NSAID
      • Question: Quick Tips
      • Answer:
        • Take with food or milk to prevent upset stomach
        • Long-term use may lead to serious complications
        • Avoid indigestion remedies within two hours
        • Avoid consuming alcohol
        • Inform doctor if liver disease
        • Regular monitoring of kidney function, liver function, and blood levels

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