Dilti SR 90 mg (Tablet (Sustained Release))

Unit Price: ৳ 3.00 (3 x 10: ৳ 90.00)
Strip Price: ৳ 30.00

Medicine Details

Category Details
Generic Diltiazem hydrochloride
Company Edruc limited

Title

  • Dilti SR Film-coated Tablet

Categories

  • Medicine
  • Healthcare
  • Pharmaceutical

Description

  • Dilti SR is indicated for the prophylaxis and treatment of chronic stable and vasopastic angina pectoris, managed alone or in combination for hypertension, effective in myocardial infarction, coronary artery spasm, arrhythmias, Raynaud's phenomenon, oesophageal motility disorder, and migraine.

DosageFormulation

  • Film-coated
  • Sustained release

DosageInstructions

  • Usual dose of Diltiazem Hydrochloride film-coated tablet is 60 mg thrice daily, may be increased to 180-300 mg/day. Sustained release formulation: doses range from 90 mg to 360 mg daily for hypertension.

ModeOfAction

  • Calcium channel antagonist
  • Peripheral and coronary vasodilator
  • Negative inotropic activity
  • Inhibits cardiac conduction
  • Antianginal effect
  • Antiarrhythmic effect
  • Antihypertensive effect

Indications

  • Prophylaxis and treatment of chronic stable and vasopastic angina pectoris
  • Management of hypertension
  • Effective in myocardial infarction, coronary artery spasm, arrhythmias, Raynaud's phenomenon, oesophageal motility disorder, and migraine

Pharmacology

  • Direct dilatation of coronary arteries and arterioles
  • Reduces oxygen requirements of myocardial tissues
  • Slowed electrophysiological activity through the S-A and A-V nodes
  • Reduces peripheral vascular resistance
  • Rapid absorption and metabolism in the liver

Interaction

  • Concomitant prophylactic therapy with short- or long-acting nitrates may be administered safely
  • Caution and careful dosage titration with drugs affecting cardiac contractility or conduction

Contraindications

  • Hypersensitivity to the drug
  • Sick sinus syndrome
  • Second or third degree AV block
  • Severe hypertension
  • Acute myocardial infarction
  • Radiographically documented pulmonary congestion

SideEffects

  • Bradycardia
  • Sino-atrial block
  • Atrioventricular block
  • Hypertension
  • Malaise
  • Headache
  • GIT disturbances
  • Oedema
  • Hepatitis
  • Depression

PregnancyLactation

  • Use during pregnancy only when potential benefits justify the possible risk to the fetus
  • Distributed into breast milk, alternative feeding method recommended for nursing women

TherapeuticClass

  • Calcium-channel blockers

StorageConditions

  • Keep out of reach of children
  • Store in cool and dry place

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