Olixar 5 mg (Tablet)
Unit Price: ৳ 2.50 (5 x 10: ৳ 125.00)
Strip Price: ৳ 25.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Olanzapine |
| Company | Everest pharmaceuticals ltd |
| Also available as |
Indications
- Treatment of schizophrenia
- Treatment of related psychoses
- Treatment of acute manic episodes in bipolar disorder
- Treatment of mixed episodes in bipolar disorder
- Treatment of psychotic features in bipolar disorder
- Treatment of rapid cycling course in bipolar disorder
Pharmacology
- Affinities for serotonin and dopamine receptors
- Mechanism of action
- Absorption after oral administration
- Absorption unaffected by food
- Non-mutagenic and non-carcinogenic
Dosage
- Initial dose of 5-10 mg once daily
- Maximum daily dosage of 20 mg
- Adjustable daily dosage based on clinical status
- Monotherapy dosage for mania
- Combination therapy dosage for schizophrenia and bipolar disorder
Administration
- Can be given without regard to meals
- Consider gradual tapering while discontinuing
Interaction
- Antagonism with levodopa and dopamine agonists
- Clearance affected by CYP1A2 inducers and inhibitors
- Increased clearance with carbamazepine
- Reduced oral bioavailability with activated charcoal
- Caution with centrally acting drugs and alcohol
Contraindications
- Hypersensitivity to any ingredient
- Known risk of narrow-angle glaucoma
Side Effects
- Somnolence
- Weight gain
- Increased appetite
- Elevated glucose levels
- Elevated triglyceride levels
- Dizziness
- Akathisia
- Parkinson's disease
- Dyskinesia
- Orthostatic hypotension
- Anticholinergic effects
- Constipation
- Dry mouth
- Asthenia
- Edema
- Photosensitivity reaction
Pregnancy & Lactation
- Use in pregnancy only if benefits justify potential risk
- No reports of teratogenicity
- Not recommended during breastfeeding
- Patients to notify physician if pregnancy occurs during treatment
Precautions & Warnings
- Cautious use in patients with history of seizures
- Cautious use in patients with low leukocyte and/or neutrophil counts
- Cautious use in patients with impaired hepatic function
- Cautious use in patients using hepatotoxic medicines
- Cautious use in patients operating hazardous machinery
- Use with patients know to increase QT interval
- Cautious use in elderly patients
Use in Special Populations
- Not studied in subjects under 18 years of age
- Starting dose for elderly patients
- Starting dose for patients with hepatic or renal impairment
Therapeutic Class
- Atypical neuroleptic drugs
Storage Conditions
- Keep below 30°C
- Keep away from light and moisture
- Keep out of the reach of children