Rapiclav (125 mg+31.25 mg)/5 ml (Powder for Suspension)

70 ml bottle: ৳ 250.00

Medicine Details

Category Details
Generic Cefuroxime axetil clavulanic acid
Company Techno drugs ltd
Also available as
Rapiclav 250 mg tablet Rapiclav 500 mg tablet

Title

Rapiclav 125 Syrup

Categories

  • Antibiotic
  • Medication
  • Pharmaceutical

Description

Rapiclav 125 Syrup is indicated for the treatment of infections caused by sensitive bacteria. It contains Cefuroxime, a bactericidal second generation cephalosporin antibiotic, and Clavulanic acid, a beta-lactamase inhibitor.

DosageForm

Syrup

DosageStrength

125 mg

DosageAdministration

  • AdolescentsAdults:
    • Pharyngitis/tonsillitis: 250 mg b.i.d. for 5-10 days
    • Acute bacterial maxillary sinusitis: 250 mg b.i.d. for 10 days
    • Acute bacterial exacerbation of chronic bronchitis: 250-500 mg b.i.d. for 10 days
  • PaediatricPatients:
    • Pharyngitis/Tonsillitis: 20 mg/kg/day b.i.d for 5-10 days
    • Acute otitis media: 30 mg/kg/day b.i.d for 10 days

Indications

  • Pharyngitis/Tonsillitis caused by Streptococcus pyogenes
  • Acute Bacterial Otitis Media caused by Streptococcus pneumoniae, Haemophilus influenzae, Moraxella catarrhalis
  • Uncomplicated skin and skin-structure infections caused by Staphylococcus aureus or Streptococcus pyogenes

Pharmacology

  • MechanismOfAction: Inhibition of bacterial cell wall synthesis
  • BactericidalActivity: Active against a wide range of Gram-positive and Gram-negative susceptible organisms

Interaction

  • ProbenecidAdministration: Increases the area under the serum concentration versus time curve by 50%

Contraindications

Known allergy to cephalosporin & Pseudomembranous Colitis

SideEffects

  • Nausea
  • Vomiting
  • Diarrhea
  • Abdominal discomfort or pain

PregnancyLactation

  • PregnancyUse: Avoid in the first trimester if possible. Safe for later pregnancy
  • LactationUse: Excreted into breast milk in small quantities

PrecautionsWarnings

  • CautionInPatientsWith: History of colitis
  • AdvisableToMonitor: Renal function if prolonged administration

TherapeuticClass

Second generation Cephalosporins

StorageConditions

Store in a cool, dry place (below 30 degrees C), away from light and moisture

CommonQuestions

  • UsesOfSyrup:
    • Treat pharyngitis, tonsillitis, sinusitis, bronchitis, SSTI, UTI, gonorrhoea, pneumonia, typhoid fever
  • OnsetOfAction: Starts working within 2-3 hours
  • DurationOfEffect: Lasts for an average duration of 4-8 hours
  • AlcoholConsumption: Unknown interaction; consult doctor before consumption
  • HabitForming: No habit-forming tendencies
  • PregnancyUsage: Safe in pregnancy after consulting doctor
  • BreastfeedingUsage: Safe in breastfeeding; enters into breastmilk at low levels
  • QuickTips:
    • Finish the full course of treatment
    • Take with food to avoid upset stomach
    • Stop taking if itchy rash, swelling, or breathing difficulties occur

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