Empadus 10 mg (Tablet)

Unit Price: ৳ 25.00 (1 x 14: ৳ 350.00)
Strip Price: ৳ 350.00

Medicine Details

Category Details
Generic Empagliflozin
Company Opsonin pharma ltd
Also available as
Empadus 25 mg tablet

Indications

  • Adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus
  • To reduce the risk of cardiovascular death in adult patients with type 2 diabetes mellitus and established cardiovascular disease

Pharmacology

  • Sodium glucose co-transporter-2 (SGLT-2) inhibitor
  • Reduces renal absorption and lowers the renal threshold for glucose
  • Contributes to reduced hyperglycaemia, weight loss, and reduced blood pressure

Dosage & Administration

  • Recommended dose: 10 mg once daily, taken in the morning, with or without food
  • Can be increased to 25 mg once daily in patients tolerating Empagliflozin
  • Correction of volume depletion prior to initiation recommended

Interactions

  • Co-administration with diuretics increases urine volume
  • Co-administration with insulin or insulin secretagogues increases the risk for hypoglycemia
  • Monitoring glycemic control with urine glucose tests is not recommended
  • Monitoring glycemic control with 1,5-AG assay is not recommended

Contraindications

  • Hypersensitivity reaction to Empagliflozin or any of its ingredients
  • Severe renal impairment, end-stage renal disease, or dialysis

Side Effects

  • Urinary tract infections
  • Female genital mycotic infections
  • Dehydration
  • Hypotension
  • Weakness
  • Dizziness
  • Increased thirstiness

Pregnancy & Lactation

  • Use during pregnancy only if potential benefit justifies potential risk to the fetus
  • Not recommended when breastfeeding

Precautions & Warnings

  • Assessment of renal function recommended prior to initiation and periodically thereafter
  • Not initiated in patients with an eGFR less than 45 ml/min/1.73 m^2
  • No dose adjustment needed in patients with an eGFR greater than or equal to 45 ml/min/1.73 m^2

Overdose Effects

  • Supportive measures such as removal of unabsorbed material, clinical monitoring, and supportive treatment should be employed
  • Removal by hemodialysis has not been studied

Therapeutic Class

  • Sodium-glucose Cotransporter-2 (SGLT2) Inhibitors

Storage Conditions

  • Keep in a cool & dry place (below 30°C), protected from light & moisture. Keep out of the reach of children

Chemical Structure

  • Molecular Formula: C23H27ClO7
  • Chemical Structure available

Common Questions

  • Reduces the reabsorption of glucose from kidney
  • Improves glycemic control in adults
  • May be unsafe to use during pregnancy
  • Probably unsafe to use during breastfeeding
  • Should be used cautiously in patients with underlying kidney disease
  • No dose adjustment needed for patients with mild to moderate liver disease
  • Used alone or together with other diabetes medicines to control blood sugar and avoid long-term complications
  • May cause dehydration, hypoglycemia, genital fungal and/or urinary tract infections, so practice good hygiene
  • Monitor blood sugar regularly while taking
  • Inform doctor immediately if experience constant dizziness, joint pain, cold-like symptoms, or unexplained nausea/vomiting

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