Zerotil 250 mg (Tablet)
Unit Price: ৳ 32.00 (2 x 7: ৳ 448.00)
Strip Price: ৳ 224.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Cefuroxime axetil |
| Company | Beacon pharmaceuticals plc |
| Also available as |
Indications
- Treatment of infections caused by sensitive bacteria
- Pharyngitis/Tonsillitis caused by Streptococcus pyogenes
- Acute Bacterial Otitis Media caused by Streptococcus pneumoniae, Haemophilus influenzae, Moraxella catarrhalis
- Acute bacterial maxillary sinusitis caused by Streptococcus pneumoniae or Haemophilus influenzae
- Lower respiratory tract infections including pneumoniae, caused by Streptococcus pneumoniae, Haemophilus influenzae, Klebsiella spp.
- Acute bacterial exacerbation of chronic bronchitis
- Secondary bacterial infections of Acute bronchitis
- Skin and skin-structure infections caused by Staphylococcus aureus or Streptococcus pyogenes
- Urinary tract infections caused by E.coli or Klebsiella pneumoniae
- Bone and Joint Infections caused by Staphylococcus aureus
- Gonorrhoea caused by penicillinase-producing and non-penicillinase producing strains of Neisseria gonorrhoeae
- Early Lyme Disease (erythema migrans) caused by Borrelia burgdorferi
Pharmacology
- Broad-spectrum bactericidal activity
- Active against β-lactamase producing strains
- Good stability to bacterial β-lactamase
Dosage
- Dosage for adolescents and adults
- Dosage for paediatric patients
- Parenteral dosage for different age groups and conditions
Administration
Freshly reconstituted solution is recommended and maintains potency for at least 24 hours at room temperature
Interaction
No potentially hazardous interactions reported
Contraindications
Contraindicated in patients with known allergy to Cephalosporins
Side Effects
- Adverse effects occurred infrequently
- Effects reported include rashes and gastrointestinal disturbances
- Prolonged use may result in the overgrowth of non susceptible organisms e.g. Candida
Pregnancy & Lactation
- US FDA pregnancy category is B
- No adequate and well-controlled studies in pregnant women
- Cefuroxime excreted in human milk
- Caution should be exercised when administered to a nursing woman
Precautions & Warnings
- Given with care to patients receiving concurrent treatment with potent diuretics & who has history of colitis
- Cephalosporin antibiotics may be given safely to patients who are hypersensitive to penicillin
- Cross reactions have been reported
Therapeutic Class
Second generation Cephalosporins
Reconstitution
Instructions for reconstitution for different intramuscular and intravenous injections
Storage Conditions
Store in a cool, dry place (below 30°C), away from light & moisture, Keep out of the reach of children