Olmepres AM 5 mg+40 mg (Tablet)
Unit Price: ৳ 17.00 (3 x 10: ৳ 509.85)
Strip Price: ৳ 169.95
Medicine Details
| Category | Details |
|---|---|
| Generic | Amlodipine besilate olmesartan medoxomil |
| Company | General pharmaceuticals ltd |
| Also available as |
Indications
- Treatment of hypertension
- Lowering blood pressure
- Initial therapy for patients likely to need multiple antihypertensive agents
- Individualized therapy based on baseline blood pressure and target goal
Pharmacology
- Amlodipine as a dihydropyridine calcium channel blocker
- Amlodipine's greater effect on vascular smooth muscle cells than on cardiac muscle cells
- Amlodipine as a peripheral arterial vasodilator
- Olmesartan Medoxomil's blocking of vasoconstrictor and aldosterone-secreting effects of angiotensin II
Dosage & Administration
- Initiate with 5/20 mg once daily for 1 to 2 weeks
- Titrate up to a maximum of 10/40 mg once daily
- Recommended starting dose of Amlodipine is 2.5 mg in patients 75 years
Interaction
- Attenuation of the antihypertensive effect by NSAIDs including selective COX-2 inhibitors
- Close monitoring of blood pressure, renal function, and electrolytes in combination therapy
Contraindications
- Co-administration with Aliskiren in patients with diabetes
Side Effects
- Peripheral edema
- Headache
- Flushing
- Dizziness
- Sprue-like enteropathy
Pregnancy & Lactation
- Pregnancy Category D
- Avoiding use in 2nd and 3rd trimester
- Potential adverse effects on the nursing infant
Precautions & Warnings
- Caution in volume- or salt-depleted patients
- Caution in patients with severe aortic stenosis
- Monitoring for increased frequency, duration, or severity of angina or acute MI in patients with severe obstructive coronary artery disease
Use in Special Populations
- Safety and effectiveness not established in pediatric patients
- No overall differences in safety or effectiveness observed between subjects 65 years of age or older and younger subjects
- No studies in patients with renal impairment
- Initial therapy not recommended in hepatically impaired patients
Overdose Effects
- No information on overdose in humans
Therapeutic Class
- Combined antihypertensive preparations
Storage Conditions
- Do not store above 30°C
- Keep away from light and out of the reach of children