Presart AM 5 mg+80 mg (Tablet)

Unit Price: ৳ 12.00 (3 x 10: ৳ 360.00)
Strip Price: ৳ 120.00

Medicine Details

Indications

  • Treatment of hypertension
  • Use as initial therapy in patients who may need multiple drugs for blood pressure goals

Pharmacology

  • Fixed dose combination of Telmisartan and Amiodipine
  • Telmisartan mechanism of action as an angiotensin receptor blocker
  • Amiodipine mechanism of action as a calcium-channel blocker

Dosage & Administration

  • Usual starting dose of 40/5 mg once daily
  • Option for larger blood pressure reductions with 80/5 mg once daily
  • Add-on Therapy for patients not controlled with single agents
  • Replacement Therapy for patients receiving separate telmisartan and amiodipine tablets

Interaction

  • Co-administration with acetaminophen, simvastatin, hydrochlorothiazide, warfarin, or ibuprofen
  • Safety with thiazide diuretics, beta-blockers, and other medications

Contraindications

  • Known hypersensitivity to the product
  • Contraindicated in pregnancy and lactation
  • Contraindicated in severe hepatic impairment, hypotension, and cardiogenic shock

Side Effects

  • Dizziness
  • Peripheral edema
  • Migraine
  • Bradycardia
  • Hypotension
  • Cough
  • Abdominal pain
  • Nausea
  • Pruritus
  • Myalgia
  • Chest pain
  • Fatigue
  • Erectile dysfunction

Pregnancy & Lactation

  • Pregnancy Categories C and D
  • Caution in nursing mothers

Precautions & Warnings

  • Avoid fetal or neonatal exposure
  • Correct volume or salt depletion before initiating therapy
  • Monitor for worsening heart failure
  • Titrate slowly in patients with hepatic or severe renal impairment

Use in Special Populations

  • Pediatric use not established
  • Caution in patients ≥75 years old
  • Caution in hepatically impaired patients

Overdose Effects

  • Manifestations of overdose with telmisartan
  • Manifestations of overdose with amiodipine

Therapeutic Class

  • Combined antihypertensive preparations

Storage Conditions

  • Do not store above 30°C
  • Protect from light and high humidity

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