Domilux 5 mg/ml (Pediatric Drops)

15 ml drop: ৳ 25.00

Medicine Details

Category Details
Generic Domperidone maleate
Company Popular pharmaceuticals ltd
Also available as
Domilux 10 mg tablet Domilux 5 mg suspension

Product Title

  • Domilux 5 mg/ml Pediatric Drop

Categories

  • Medicine
  • Pharmaceuticals

Description

  • Dopamine antagonist medication used to treat dyspeptic symptom complex, acute nausea and vomiting, Parkinson's disease, and to aid radiological studies

Dimensions

  • N/A

Color Options

  • N/A

Functions

  • Relieves nausea and vomiting
  • Facilitates gastric emptying
  • Enhances antral and duodenal peristalsis
  • Regulates contraction of the pylorus
  • Increases esophageal peristalsis
  • Restores normal motility and tone of the upper gastrointestinal tract

Materials

  • Domperidone

Technical Specifications

  • Molecular Formula: C22H24ClN5O2

Design Elements

  • Chemical Structure

Usability Features

  • Should be taken 15-30 minutes before meals

Dosage & Administration

  • Adults: 10-20 mg (1-2 tablets or 10-20 ml suspension) every 6-8 hours daily
  • Children: 2-4 ml suspension/10 kg body weight every 6-8 hours daily

Interaction

  • Concomitant administration of anticholinergic drugs may antagonize the antidyspeptic effect of domperidone
  • Antacids and antisecretory drugs should not be given simultaneously with domperidone
  • Main metabolic pathway through CYP3A4
  • In vitro data suggest concomitant use of drugs that significantly inhibit CYP3A4 may increase plasma levels of domperidone

Contraindications

  • Known hypersensitivity to domperidone
  • Neonates
  • Gastrointestinal hemorrhage, mechanical obstruction or perforation
  • Prolactin releasing pituitary tumor (prolactinoma)

Side Effects

  • Transient intestinal cramps
  • Rare extrapyramidal phenomena
  • Increase in plasma prolactin level
  • Rare allergic reactions such as rash and urticaria

Pregnancy & Lactation

  • Should only be used during the first trimester of pregnancy if justified by therapeutic benefit
  • Not known whether excreted in breast milk is harmful to the newborn
  • Nursing not recommended unless expected benefits outweigh potential risk

Precautions & Warnings

  • Absolute caution in children due to increased risk of extrapyramidal reactions
  • Use with caution in patients with hepatic impairment

Special Populations

  • Use with caution in infants due to immature blood-brain barrier
  • Use with caution in patients with hepatic impairment
  • Dosing frequency may need to be reduced in patients with severe renal insufficiency

Overdose Effects

  • Symptoms may include drowsiness, disorientation, and extrapyramidal reactions
  • Administration of activated charcoal and close observation recommended

Therapeutic Class

  • Motility Stimulants
  • Dopamine antagonist
  • Prokinetic drugs

Storage Conditions

  • Store below 30°C
  • Protected from light & moisture
  • Keep out of children's reach

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