Osmina 60 mg (Tablet)
Unit Price: ৳ 30.00 (2 x 10: ৳ 600.00)
Strip Price: ৳ 300.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Ospemifene |
| Company | Navana pharmaceuticals ltd |
Indications
- Estrogen agonist/antagonist
- Treatment of dyspareunia
- Vulvar and vaginal atrophy
- Menopause symptom relief
Pharmacology
- Next-generation SERM
- Estrogen receptor modulator
- Agonistic effect on endometrium
Dosage & Administration
- 60 mg tablet
- Once daily with food
- Treatment of dyspareunia
- Treatment of vaginal dryness
Interaction
- Metabolized by CYP3A4 and CYP2C9
- Contraindicated with estrogens and estrogen agonists/antagonists
- Interactions with fluconazole, rifampin, ketoconazole, warfarin
- Highly protein-bound
- Enzyme inhibition risk
Contraindications
- Abnormal genital bleeding
- Estrogen-dependent neoplasia
- DVT and pulmonary embolism history
- Hypersensitivity
- Pregnancy
Side Effects
- Cardiovascular disorders
- Malignant neoplasms
- Hot flush
- Vaginal discharge
- Muscle spasms
- Hyperhidrosis
Pregnancy & Lactation
- Contraindicated in pregnancy
- Likely risk of adverse outcomes during pregnancy and labor
- Unknown excretion in breast milk
- Not recommended during lactation
Precautions & Warnings
- Cardiovascular risk management
- Stroke incidence rates
- Coronary heart disease risks
- Venous thromboembolism precautions
- Endometrial and breast cancer risks
- Severe hepatic impairment contraindication
- Hypersensitivity reactions
- Vaginal bleeding importance
- Hot flashes occurrence
- Carcinogenesis and mutagenesis concerns
- Fertility impairment effects
Use in Special Populations
- Not indicated in children
- No clinically meaningful differences in geriatric use
- Renal impairment pharmacokinetics
- Severe hepatic impairment contraindication
Therapeutic Class
- Drugs used in vaginal and vulval conditions
Storage Conditions
- Keep below 30°C
- Protect from light and moisture
- Keep out of reach of children