Cardil 60 mg (Tablet)

Title

• Cardil Film-Coated Tablet

Categories

• Medicine
• Healthcare
• Pharmaceuticals

Description

• Prophylaxis and treatment of chronic stable and vasospastic angina pectoris
• Management of hypertension
• Treatment of myocardial infarction and arrhythmias
• Pharmacological actions: antianginal, antiarrhythmic, and antihypertensive

Color options

• Film-coated formulation: no color options mentioned

Dimensions

• Tablet size: standard pharmaceutical tablet size

Functions

• Vasodilation of coronary arteries
• Reduces systemic pressure of cardiac 'after load'
• Reduces oxygen requirements of myocardial tissues
• Slows electrophysiological activity at cardiac nodes
• Reduces peripheral vascular resistance

Materials

• Diltiazem hydrochloride as the active ingredient

Technical specifications

• Usual dose: 60 mg thrice daily
• Dosage may be increased to 180-300 mg/day if necessary
• Peak plasma concentration reaches within 30-60 minutes
• Metabolized in the liver and excreted through bile

Design elements

• Film-coated formulation
• Sustained release formulation

Usability features

• Usable for prophylaxis and treatment of angina pectoris and hypertension
• Usable for some selected supraventricular tachyarrhythmias

Mode of action

• Calcium channel antagonist
• Peripheral and coronary vasodilator
• Inhibits cardiac conduction at the sino-atrial and atrioventricular nodes

Dosage and administration

• Film-coated formulation: Usual dose is 60 mg thrice daily, may be increased to 180-300 mg/day
• Sustained release formulation: Initial dose 90 mg or 120 mg twice daily, up to 360 mg daily may be required

Interaction

• Concomitant therapy with short- or long-acting nitrates may be administered safely
• Caution and careful dosage titration when used concomitantly with other drugs affecting cardiac contractility or conduction

Contraindications

• Contraindicated in patients with known hypersensitivity to the drug
• Contraindicated in sick sinus syndrome, second or third degree AV block, and severe hypertension

Side effects

• Bradycardia
• Sino-atrial block
• Atrioventricular block
• Hypertension
• Malaise
• Headache
• GIT disturbances
• Oedema
• Hepatitis
• Depression

Pregnancy and lactation

• No adequate and controlled studies in pregnant women
• Distributed into breast milk, not recommended for breastfeeding women

Therapeutic class

• Calcium-channel blockers

Storage conditions

• Store in a cool and dry place
• Keep out of reach of children

Related Brands

• Cardizem 30 mg (Tablet) - drug-international-ltd
• Cardizem 60 mg (Tablet) - drug-international-ltd
• Cardizem SR 120 mg (Tablet (Sustained Release)) - drug-international-ltd
• Diltizem SR 90 mg (Tablet (Sustained Release)) - square-pharmaceuticals-plc
• Cardizem SR 90 mg (Tablet (Sustained Release)) - drug-international-ltd