Telisa-A 5 mg+80 mg (Tablet)
Unit Price: ৳ 18.00 (3 x 10: ৳ 540.00)
Strip Price: ৳ 180.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Amlodipine besilate telmisartan |
| Company | Acme laboratories ltd |
| Also available as |
Therapeutic Class
- Combined antihypertensive preparations
Indications
- Treatment of hypertension
- Initial therapy for blood pressure control
Pharmacology
- Fixed dose combination of Telmisartan and Amiodipine
- Telmisartan - non-peptide angiotensin receptor blocker (ARB)
- Amiodipine - dihydropyridine calcium-channel blocker (CCB)
Dosage & Administration
- Usual starting dose of 40/5 mg once daily
- Maximum recommended dose of 80/10 mg once daily
- Options for initial therapy, add-on therapy, and replacement therapy
Interaction
- No clinically significant interaction with various drugs
- Possible inhibition of CYP2C19 metabolism by Telmisartan
Contraindications
- Hypersensitivity to product components
- Pregnancy & lactation
- Biliary obstructive disorders
- Severe hepatic impairment
- Hypotension
- Cardiogenic shock
- Left ventricle outflow tract obstruction
Side Effects
- Dizziness
- Peripheral edema
- Migraine
- Headache
- Bradycardia
- Hypotension
- Cough
- Abdominal pain
- Diarrhea
- Nausea
- Myalgia
- Erectile dysfunction
- Chest pain
- Fatigue
Pregnancy & Lactation
- Pregnancy Categories C and D
- Recommendation to discontinue nursing if taking the drug
Precautions & Warnings
- Avoid fetal or neonatal exposure
- Correct volume or salt depletion before initiating therapy
- Monitor for signs and symptoms of hypotension
- Monitor for worsening of heart failure
- Avoid concomitant use of ACE inhibitor and angiotensin receptor blocker
- Be cautious when initiating in patients with severe obstructive coronary artery disease
Use in Special Populations
- No established safety and effectiveness in pediatric patients
- Not recommended for patients ≥75 years old
- Not recommended for hepatically impaired patients
Overdose Effects
- Manifestations of overdose with Telmisartan - hypotension, dizziness, tachycardia
- Manifestations of overdose with Amiodipine - excessive vasodilation, hypotension, reflex tachycardia
- Necessity for supportive treatment and cardiovascular monitoring
Storage Conditions
- Do not store above 30°C
- Protect from light and high humidity
- Keep out of the reach of children