Cardizem 30 mg (Tablet)
Unit Price: ৳ 3.05 (7 x 14: ৳ 298.90)
Strip Price: ৳ 42.70
Medicine Details
| Category | Details |
|---|---|
| Generic | Diltiazem hydrochloride |
| Company | Drug international ltd |
| Also available as |
Indications
- Prophylaxis of chronic stable and vasopastic angina pectoris
- Treatment of hypertension
- Management of myocardial infarction
- Treatment of coronary artery spasm
- Management of arrhythmias
- Treatment of Raynaud's phenomenon
- Care of oesophageal motility disorder
- Management of migraine
- Prophylaxis of angina pectoris
- Management of essential hypertension
- Prophylaxis of supraventricular tachyarrhythmias
Pharmacology
- Calcium channel antagonist
- Peripheral and coronary vasodilator
- Negative inotropic activity
- Inhibition of cardiac conduction
- Reduced systemic pressure of cardiac afterload
- Reduced oxygen requirements of myocardial tissues
- Reduction of peripheral vascular resistance
- Rapid absorption
- High protein binding
- Liver metabolism
- Bile excretion
Dosage & Administration
- Usual dose of 60 mg thrice daily for film-coated tablet
- Initial dose of 90 mg or 120 mg twice daily for sustained release formulation
- Dosage adjustment based on patient response
- Higher doses for unstable angina
- Special dosing for elderly and patients with impaired hepatic or renal function
- Regular heart rate measurement for dosage management
Interaction
- Concomitant prophylactic therapy with nitrates
- Caution and careful dosage titration with drugs affecting cardiac contractility and conduction
Contraindications
- Hypersensitivity to the drug
- Sick sinus syndrome
- Second or third degree AV block
- Severe hypertension
- Acute myocardial infarction
- Radiographically documented pulmonary congestion
Side Effects
- Bradycardia
- Sino-atrial block
- Atrioventricular block
- Hypertension
- Malaise
- Headache
- Hot flushes
- Gastrointestinal disturbances
- Edema
- Hepatitis
- Depression
Pregnancy & Lactation
- Use during pregnancy only when potential benefits justify possible risk to the fetus
- Avoid breastfeeding while receiving the drug
- Consider alternative infant feeding methods
Therapeutic Class
- Calcium-channel blockers
Storage Conditions
- Keep out of reach of children
- Store in a cool and dry place