Cardizem 60 mg (Tablet)

Unit Price: ৳ 5.05 (10 x 10: ৳ 505.00)
Strip Price: ৳ 50.50

Medicine Details

Indications

  • Prophylaxis and treatment of angina pectoris
  • Management of hypertension
  • Treatment of myocardial infarction
  • Management of Raynaud's phenomenon
  • Treatment of migraine
  • Management of oesophageal motility disorder

Pharmacology

  • Calcium channel antagonist
  • Peripheral and coronary vasodilator
  • Negative inotropic activity
  • Inhibition of cardiac conduction
  • Antianginal action
  • Antiarrhythmic action
  • Antihypertensive action
  • High protein binding
  • Rapid absorption
  • Liver metabolism
  • Bile excretion

Dosage & Administration

  • Usual dose of 60mg thrice daily for film-coated formulation
  • Initial dose of 90mg or 120mg twice daily for sustained release formulation
  • Dosage requirements vary between patients
  • Dose adjustment for elderly and patients with impaired hepatic or renal function

Interaction

  • Safe administration with short- or long-acting nitrates
  • Caution with other drugs affecting cardiac contractility or conduction

Contraindications

  • Hypersensitivity to the drug
  • Sick sinus syndrome
  • Second or third degree AV block
  • Severe hypertension
  • Acute myocardial infarction
  • Radiographically documented pulmonary congestion

Side Effects

  • Bradycardia
  • Sino-atrial block
  • Atrioventricular block
  • Hypertension
  • Malaise
  • Headache
  • GIT disturbances
  • Oedema
  • Hepatitis
  • Depression

Pregnancy & Lactation

  • Use during pregnancy if benefits justify risk to fetus
  • Avoid breastfeeding while using diltiazem

Therapeutic Class

  • Calcium-channel blockers

Storage Conditions

  • Store in a cool and dry place
  • Keep out of reach of children

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