Goutex 300 mg (Tablet)
Unit Price: ৳ 8.00 (3 x 10: ৳ 240.00)
Strip Price: ৳ 80.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Allopurinol |
| Company | Biopharma limited |
| Also available as |
Indications
- Reducing urate/uric acid formation
- Managing 2,8-dihydroxyadenine (2,8-DHA) renal stones
- Managing recurrent mixed calcium oxalate renal stones
Pharmacology
- Xanthine oxidase inhibitor
- Acts on purine catabolism
- Reduces the production of uric acid
- Approximately 90% absorbed from the GI tract
Dosage & Administration
- Initiate at low dosage for adults
- Different dosage schedules based on condition severity
- Specific dosage for children and elderly
- Dosage adjustment for renal impairment
Interaction
- Influence on 6-mercaptopurine and azathioprine
- Impact on plasma half-life of vidarabine
- Monitoring needed for theophylline levels
- Potential increase in skin rash with concurrent ampicillin or amoxicillin use
- Possible increase in ciclosporin plasma concentration
Contraindications
- Contra-indicated in patients with known hypersensitivity to allopurinol
Side Effects
- Rashes
- Gastrointestinal disorders
- Malaise
- Hypertension
- Hepatotoxicity
- Neuropathy
- Gynaecomastia
- Blood disorders
Pregnancy & Lactation
- Inadequate evidence of safety in human pregnancy
- Use only when no safer alternative is available
- No data on effects on breastfed baby
Precautions & Warnings
- Immediate withdrawal if skin rash or sensitivity occurs
- Reduced doses for hepatic or renal impairment
- Caution in patients under treatment for hypertension or cardiac insufficiency
Overdose Effects
- Reported ingestion of up to 22.5g without adverse effect
- Symptoms include nausea, vomiting, diarrhoea, and dizziness
- Facilitates excretion via hydration and haemodialysis if necessary
Therapeutic Class
- Drugs used in Gout
Storage Conditions
- Keep below 30°C temperature
- Away from light and moisture
- Keep out of the reach of children