Ucorex 100 mg (Tablet)
Unit Price: ৳ 4.54 (5 x 10: ৳ 227.24)
Strip Price: ৳ 45.45
Medicine Details
| Category | Details |
|---|---|
| Generic | Allopurinol |
| Company | Healthcare pharmaceuticals ltd |
Indications
- Reducing urate/uric acid formation
- Manage gouty arthritis
- Manage skin tophi
- Manage nephrolithiasis
- Manage 2,8-dihydroxyadenine renal stones
- Management of recurrent mixed calcium oxalate renal stones
Pharmacology
- Xanthine oxidase inhibitor
- Oral administration
- Reduces production of uric acid
- Structural analogue of hypoxanthine
- Approximately 90% absorbed from GI tract
- Plasma half life of 1 to 2 hours
Dosage & Administration
- Low dosage initiation for adults
- Dosage adjustment based on serum urate response
- Different dosage schedules for mild, moderately severe, and severe conditions
- Specific dosage for children and elderly
- Dosage adjustment in renal impairment
Interaction
- Potential interaction with 6-mercaptopurine and azathioprine
- Enhanced toxic effects with vidarabine
- Monitoring theophylline levels
- Increased frequency of skin rash with ampicillin or amoxicillin
- Potential increase in ciclosporin plasma concentration
Contraindications
- Contra-indicated in known hypersensitivity to allopurinol
Side Effects
- Rashes
- Gastrointestinal disorders
- Malaise
- Headache
- Vertigo
- Drowsiness
- Visual and test disturbances
- Hypertension
- Alopecia
- Hepatotoxicity
- Neuropathy
- Gynecomastia
- Blood disorders
Pregnancy & Lactation
- Inadequate evidence of safety in human pregnancy
- Use in pregnancy only when no safer alternative
- No data concerning effects on breast-fed baby
Precautions & Warnings
- Immediate withdrawal in case of skin rash or sensitivity
- Reduced doses in hepatic or renal impairment
- Use with caution in patients with hypertension or cardiac insufficiency
Overdose Effects
- Ingestion effects including nausea, vomiting, and dizziness
- Adequate hydration for optimum diuresis
- Haemodialysis as necessary
Therapeutic Class
- Drugs used in Gout
Storage Conditions
- Keep below 30°C temperature
- Away from light and moisture
- Keep out of the reach of children