Amlohil 5 mg (Tablet)

Unit Price: ৳ 4.50 (5 x 10: ৳ 225.00)
Strip Price: ৳ 45.00

Medicine Details

Category Details
Generic Amlodipine besilate
Company Goodman pharmaceuticals ltd
Also available as
Amlohil 10 mg tablet

Indications

  • Essential hypertension
  • Angina pectoris
  • Vasospastic angina

Mode of Action

Amlodipine is a dihydropyridine calcium-channel blocker, with a long duration of action, used for the treatment of hypertension and angina pectoris.

Dosage & Administration

  • Hypertension: Usual dose is 5 mg once daily. The maximum dose is 10 mg once daily.
  • Angina: 5 to 10 mg, using the lower dose for elderly and in patients with hepatic insufficiency.

Interaction

  • Potentially hazardous interactions: The combination of Amlohil and p-blockers should be avoided in patients with markedly impaired cardiac left ventricular function.
  • Other Significant Interactions:
    • Digoxin
    • Cimetidine
    • Warfarin
    • Food

Contraindications

  • Hypersensitivity to dihydropyridine derivatives
  • Pregnant woman

Side Effects

  • Dizziness
  • Flushing
  • Headache
  • Hypotension
  • Peripheral edema
  • Gastrointestinal disturbances
  • Increased micturition frequency
  • Lethargy
  • Eye pain
  • Mental depression
  • Rashes
  • Fever
  • Abnormalities in liver function

Pregnancy & Lactation

  • Pregnancy Category: C
  • Recommendation for Nursing: It is recommended that nursing be discontinued while Amlodipine is administered.

Precautions & Warnings

  • Precaution should be taken in patients with hepatic impairment and during pregnancy and breast feeding.

Use in Special Populations

  • Children with hypertension: 2.5 mg once daily as a starting dose, up-titrated to 5 mg once daily if blood pressure goal is not achieved after 4 weeks.
  • Elderly: Normal dosage regimens are recommended in the elderly, but increase of the dosage should take place with care.
  • Renal impairment: Normal dosage is recommended. Amlohil is not dialysable.
  • Hepatic impairment: Dose selection should be cautious and should start at the lower end of the dosing range.

Overdose Effects

  • Symptoms: Excessive peripheral vasodilatation, reflex tachycardia, marked and probably prolonged systemic hypotension up to and including shock with fatal outcome
  • Management: Clinically significant hypotension due to amlodipine overdosage calls for active cardiovascular support, elevation of extremities, attention to circulating fluid volume and urine output

Therapeutic Class

Calcium-channel blockers

Storage Conditions

Store in a cool & dry place, protected from light.

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