Amlovas 10 mg (Tablet)
Unit Price: ৳ 8.00 (3 x 10: ৳ 240.00)
Strip Price: ৳ 80.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Amlodipine besilate |
| Company | Popular pharmaceuticals ltd |
| Also available as |
Indications
- Treatment of essential hypertension
- Treatment of chronic stable angina pectoris
- Treatment of confirmed or suspected vasospastic angina
Pharmacology
- Dihydropyridine calcium-channel blocker
- Long duration of action
- Influences myocardial cells
- Vasodilation resulting in reduced peripheral resistance
- Increased coronary blood flow
- Reflex increase in coronary heart rate
- Increased myocardial oxygen supply
Dosage & Administration
- Usual dose for hypertension: 5 mg once daily
- Maximum dose for hypertension: 10 mg once daily
- Usual dose for angina: 5-10 mg once daily
- Administration without regard to meals
Interaction
- Potentially hazardous interactions with p-blockers
- No interaction between Amlodipine and Digoxin
- No interaction between Amlodipine and Cimetidine
- Amlodipine did not significantly alter the effect of Warfarin on prothrombin time
- Food does not alter the rate or extent of absorption of Amlodipine
Contraindications
- Hypersensitivity to dihydropyridine derivatives
- Pregnancy
Side Effects
- Dizziness
- Flushing
- Headache
- Hypotension
- Peripheral edema
- Gastrointestinal disturbances
- Increased micturition frequency
- Lethargy
- Eye pain
- Mental depression
- Paradoxical increase in ischaemic chest pain
- Excessive fall in blood pressure
- Rashes
- Fever
- Abnormalities in liver function
Pregnancy & Lactation
- Pregnancy Category C
- Use during pregnancy only if potential benefit justifies potential risk to fetus
- Recommendation to discontinue nursing while Amlodipine is administered
Precautions & Warnings
- Precaution in patients with hepatic impairment
- Precaution during pregnancy and breast feeding
Use in Special Populations
- Dosing recommendations for children with hypertension
- Safety not established for children under 6 years old
- Normal dosage regimens recommended for elderly
- Normal dosage recommended for renal impairment
- Caution in dose selection for patients with mild to moderate hepatic impairment
- Initiation at lowest dose for patients with severe hepatic impairment
Overdose Effects
- Excessive peripheral vasodilatation
- Reflex tachycardia
- Marked and probably prolonged systemic hypotension up to and including shock
- Active cardiovascular support required
- Management with vasoconstrictor, intravenous calcium gluconate, or gastric lavage
Therapeutic Class
- Calcium-channel blockers
Storage Conditions
- Keep out of reach of children
- Store in a cool and dry place
- Protect from light