CVnor 10 mg (Tablet)

Unit Price: ৳ 6.00 (3 x 10: ৳ 180.00)
Strip Price: ৳ 60.00

Medicine Details

Category Details
Generic Amlodipine besilate
Company Navana pharmaceuticals ltd
Also available as

Indications

  • Essential hypertension
  • Angina pectoris
  • Vasospastic angina

Pharmacology

  • Calcium-channel blocker
  • Vasodilation
  • Blood pressure reduction
  • Coronary blood flow increase

Dosage & Administration

  • Usual dose 5 mg once daily for hypertension
  • Usual dose 5-10 mg for angina
  • May be taken without regard to meals

Interaction

  • Avoid combination with p-blockers in impaired cardiac left ventricular function
  • No significant interactions with Digoxin, Cimetidine, Warfarin or food

Contraindications

  • Hypersensitivity to dihydropyridine derivatives
  • Pregnancy

Side Effects

  • Dizziness
  • Flushing
  • Headache
  • Hypotension
  • Peripheral edema
  • Gastrointestinal disturbances
  • Increased micturition frequency
  • Lethargy
  • Eye pain
  • Mental depression
  • Ischaemic chest pain
  • Excessive fall in blood pressure
  • Rashes
  • Fever
  • Abnormalities in liver function

Pregnancy & Lactation

  • Pregnancy Category C
  • Use justified only if benefit outweighs risk
  • Discontinue nursing while administered

Precautions & Warnings

  • Caution in patients with hepatic impairment
  • Caution during pregnancy and breastfeeding

Use in Special Populations

  • Specific dosing for children with hypertension
  • Elderly well tolerated at similar doses
  • Normal dosage in renal impairment
  • Caution and lower dose in mild to moderate hepatic impairment
  • Initiate at lowest dose in severe hepatic impairment

Overdose Effects

  • Excessive peripheral vasodilatation
  • Reflex tachycardia
  • Marked systemic hypotension
  • Management with cardiovascular support and fluid volume attention
  • Use of vasoconstrictor and intravenous calcium gluconate
  • Potential benefit of gastric lavage and charcoal use
  • Dialysis not likely to be of benefit

Therapeutic Class

  • Calcium-channel blockers

Storage Conditions

  • Keep out of reach of children
  • Store in cool, dry place, protected from light

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