Vasopin 10 mg (Tablet)
Unit Price: ৳ 5.03 (3 x 10: ৳ 151.00)
Strip Price: ৳ 50.33
Medicine Details
| Category | Details |
|---|---|
| Generic | Amlodipine besilate |
| Company | Silva pharmaceuticals ltd |
| Also available as |
Indications
- Essential hypertension
- Angina pectoris
- Vasospastic angina
Pharmacology
- Dihydropyridine calcium-channel blocker
- Long duration of action
- Vasodilation
- Reduced peripheral resistance
- Increased coronary blood flow
- Reflex increase in coronary heart rate
Dosage & Administration
- Usual dose is 5 mg once daily for hypertension
- Usual dose is 5 to 10 mg for angina
- May be taken without regard to meals
Interaction
- Potentially hazardous interactions with p-blockers
- No interaction between Vasopin and Digoxin
- No interaction between Vasopin and Cimetidine
- No significant alteration of Warfarin effect on prothrombin time
- Food does not alter the rate or extent of absorption of Vasopin
Contraindications
- Hypersensitivity to dihydropyridine derivatives
- Pregnancy
Side Effects
- Dizziness
- Flushing
- Headache
- Hypotension
- Peripheral edema
- Gastrointestinal disturbances
- Increased micturition frequency
- Lethargy
- Eye pain
- Mental depression
- Ischaemic chest pain
- Excessive fall in blood pressure
- Rashes
- Fever
- Abnormalities in liver function
Pregnancy & Lactation
- Pregnancy Category C
- Amlodipine excretion in human milk is not known
- Discontinue nursing while Amlodipine is administered
Precautions & Warnings
- Hepatic impairment precautions
- Pregnancy and breast feeding precautions
Use in Special Populations
- Dosing for children with hypertension
- Effect on blood pressure in patients less than 6 years of age is not known
- Elderly dosage regimens
- No correlation of dose with renal impairment
- Dosage recommendations for hepatic impairment
Overdose Effects
- Excessive peripheral vasodilatation
- Reflex tachycardia
- Systemic hypotension up to and including shock
- Active cardiovascular support required
- Elevation of extremities
- Attention to circulating fluid volume and urine output
- Use of vasoconstrictor
- Intravenous calcium gluconate may be beneficial
- Gastric lavage may be worthwhile
- Use of charcoal to reduce absorption rate
- Dialysis is not likely to be of benefit
Therapeutic Class
- Calcium-channel blockers
Storage Conditions
- Store in a cool & dry place
- Protected from light