Cardifort Plus 5 mg+25 mg (Tablet)
Unit Price: ৳ 5.25 (3 x 10: ৳ 157.50)
Strip Price: ৳ 52.50
Medicine Details
| Category | Details |
|---|---|
| Generic | Amlodipine besilate atenolol |
| Company | Nuvista pharma ltd |
| Also available as |
Indications
- Essential hypertension
- Angina pectoris & hypertension co-existing diseases
- Post Myocardial Infarction (MI) patients
- Refractory angina pectoris with failed nitrate therapy
Pharmacology
- Fixed-dose combination of Amlodipine and Atenolol
- Amlodipine is a dihydropyridine calcium antagonist
- Amlodipine acts as a peripheral vasodilator
- Atenolol is a cardioselective beta-blocker
- Atenolol causes reduction in blood pressure and myocardial oxygen demand
Dosage & Administration
- Recommended dosage: Amlodipine and Atenolol 5/25 mg tablet once daily
- Dosage may be increased as advised by physicians
- Dosage should be individualized
Interaction
- Disopyramide: Atenolol reduces the clearance of disopyramide by 20%
- Ampicillin at high doses may reduce Atenolol levels
- Oral antidiabetics and insulin: Beta-blockers may decrease tissue sensitivity to insulin and inhibit insulin secretion
Contraindications
- Hypersensitivity to either component
- Sinus bradycardia
- Second and higher degrees of heart block
- Cardiogenic shock
- Hypotension
- Congestive heart failure
- Poor left ventricular function
Side Effects
- Fatigue
- Headache
- Edema
- Nausea
- Drowsiness
- Anxiety
- Depression
Pregnancy & Lactation
- Use during pregnancy only if benefit outweighs potential fetal risk
- Not recommended for nursing mothers
- Breast-feeding should be stopped if use is considered necessary
Precautions & Warnings
- Use with caution in patients with airway obstruction
- Can be used in patients with renal impairment
- Caution in patients with severe liver damage
- Patients should be warned against stopping the drug suddenly
Overdose Effects
- Hypotension
- Congestive cardiac failure in overdosage cases
- Unabsorbed drugs may be removed by gastric lavage or charcoal administration
- Symptomatic treatment suggested
Therapeutic Class
- Combined antihypertensive preparations
Storage Conditions
- Keep below 30°C temperature
- Keep away from light and moisture
- Keep out of the reach of children