Diltizem SR 90 mg (Tablet (Sustained Release))

Unit Price: ৳ 5.63 (4 x 10: ৳ 225.20)

Strip Price: ৳ 56.30

Medicine Details

Category	Details
Generic	Diltiazem hydrochloride
Company	Square pharmaceuticals plc

Prophylaxis and treatment of chronic stable and vasopastic angina pectoris
Management of hypertension
Treatment of myocardial infarction, coronary artery spasm, arrhythmias, Raynaud's phenomenon, oesophageal motility disorder, and migraine
Calcium channel antagonist with peripheral and coronary vasodilator activity
Reduced systemic pressure of cardiac 'after load'
Reduced oxygen requirements of myocardial tissues
Effective in slowing electrophysiological activity through the S-A and A-V nodes
Reduction of peripheral vascular resistance
Rapid absorption with high protein binding
Metabolism in the liver with excretion through bile

Usual dose of 60 mg thrice daily for film-coated formulation
Divided dose may be increased to 180-300 mg/day if necessary
Starting dose of 60 mg twice daily for elderly and patients with impaired hepatic or renal function
Mild to moderate hypertension: initially 90 mg or 120 mg twice daily; up to 360 mg daily may be required
Angina: initially 90 mg or 120 mg twice daily in divided doses
Maximum dose of 480 mg/day in some patients, especially in unstable angina
Recommended caution and careful dosage titration for concomitant use with other drugs affecting cardiac contractility and/or conduction

Concomitant prophylactic therapy with short- or long-acting nitrates may be administered safely
Caution and careful dosage titration recommended when administered concomitantly with other drugs affecting cardiac contractility

No adequate and controlled studies in pregnant women
Use during pregnancy only when potential benefits justify possible risk to the fetus
Distribution into breast milk
Breastfeeding not recommended during diltiazem therapy